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Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside

Nanomedicine is among the most promising emerging fields that can provide innovative and radical solutions to unmet needs in pharmaceutical formulation development. Encapsulation of active pharmaceutical ingredients within nano-size carriers offers several benefits, namely, protection of the therape...

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Formato: Online
Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2022
Assuntos:
poly(lactic-co-glycolic acid) (PLGA)
blood–brain barrier (BBB)
current Good Manufacturing Practice (cGMP)
Food and Drug Administration (FDA)
nanotechnology
PLGA nanoparticles
neurodegenerative diseases
drug delivery
central nervous system
neuroprotective drugs
fluorescent labeling
DiI
coumarin 6
rhodamine 123
Cy5.5
quantum yield
brightness
stability of fluorescent label
confocal microscopy
intracellular internalization
in vivo neuroimaging
double-emulsion method
dry powder inhalation
antigen release
porous PLGA particles
microfluidics
methotrexate
chitosan
PLA/PLGA
sustained release
micro-implant
animal model
minimally invasive
drug delivery system
nanoparticles
poly (lactic-co-glycolic acid) (PLGA)
microfluidic
pharmacokinetics (PK) and biodistribution
atorvastatin calcium
poly(lactide-co-glycolide)
polymeric nanoparticles
carrageenan induced inflammation
anti-inflammatory
radiolabeled nanoparticles
nuclear medicine
photothermal therapy
phthalocyanine
SKOVip-kat
Katushka
TurboFP635
JO-4
PLGA
orthotopic tumors
3D culture
spheroids
poly(lactic-co-glycolic acid)
nanomedicine
scale-up manufacturing
clinical translation
inline sonication
tangential flow filtration
lyophilization
downstream processing
H. pylori
design of experiments
poly(lactic-co-glycolic) acid
size
cancer
chemoimmunotherapy
immunogenic cell death
immune checkpoint blockade
PNA5 glycopeptide
mas receptor
angiotensin
PLGA diblock copolymer
ester and acid-end capped
double emulsion solvent evaporation
biocompatible
biodegradable
cardiovascular
nanoparticle
solid-state characterization
in vitro
drug release kinetics modeling
PEGylation
amine
emulsion
polyvinyl alcohol (PVA)
Pluronic triblock copolymer
trehalose
sucrose
Indomethacin
solvents
stabilizers
morphology
particle-size
encapsulation
drug release
cytotoxicity
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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