Antiphospholipid Syndrome
Antiphospholipid syndrome (APS) is an acquired autoimmune disorder in which the immune system mistakenly produces antiphospholipid antibodies that attack tissues in the body. These antibodies can lead to the formation of blood clots in arteries and veins. During pregnancy, APS can also lead to misca...
Salvato in:
| Natura: | Online |
|---|---|
| Lingua: | inglese |
| Pubblicazione: |
IntechOpen
2022
|
| Soggetti: | |
| Accesso online: | ONIX_20220727_9781839690549_172 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1869519168632520704 |
|---|---|
| collection | Directory of Open Access Books |
| description | Antiphospholipid syndrome (APS) is an acquired autoimmune disorder in which the immune system mistakenly produces antiphospholipid antibodies that attack tissues in the body. These antibodies can lead to the formation of blood clots in arteries and veins. During pregnancy, APS can also lead to miscarriage and stillbirth. Classification criteria require a clinical event (i.e., thrombosis or pregnancy complication) and persistent positive blood test results at least three months apart that detect lupus anticoagulant, anti-cardiolipin antibodies, or anti-β2-glycoprotein-1 antibodies. This book addresses important clinical aspects of APS, including stroke and APS, obstetric manifestations of APS, and bleeding complications in APS. It also discusses the diagnostic utility of a novel autoantibody against β2-glycoprotein I/HLA class II complexes as a promising biomarker for APS. Finally, this book also reviews the latest findings in the field of extracellular vesicles in APS and provides explanations of their role in the pathogenesis of APS. |
| format | Online |
| id | doab-20.500.12854ir-90276 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-902762024-03-31T22:44:07Z Antiphospholipid Syndrome Žigon, Polona Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology Antiphospholipid syndrome (APS) is an acquired autoimmune disorder in which the immune system mistakenly produces antiphospholipid antibodies that attack tissues in the body. These antibodies can lead to the formation of blood clots in arteries and veins. During pregnancy, APS can also lead to miscarriage and stillbirth. Classification criteria require a clinical event (i.e., thrombosis or pregnancy complication) and persistent positive blood test results at least three months apart that detect lupus anticoagulant, anti-cardiolipin antibodies, or anti-β2-glycoprotein-1 antibodies. This book addresses important clinical aspects of APS, including stroke and APS, obstetric manifestations of APS, and bleeding complications in APS. It also discusses the diagnostic utility of a novel autoantibody against β2-glycoprotein I/HLA class II complexes as a promising biomarker for APS. Finally, this book also reviews the latest findings in the field of extracellular vesicles in APS and provides explanations of their role in the pathogenesis of APS. 2022-07-27T08:17:56Z 2022-07-27T08:17:56Z 2022 book ONIX_20220727_9781839690549_172 9781839690549 9781839690532 9781839690556 https://directory.doabooks.org/handle/20.500.12854/90276 eng image/jpeg n/a https://www.intechopen.com/books/10322 https://mts.intechopen.com/storage/books/10322/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.91508 10.5772/intechopen.91508 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781839690549 9781839690532 9781839690556 IntechOpen 142 open access |
| spellingShingle | Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology Antiphospholipid Syndrome |
| title | Antiphospholipid Syndrome |
| title_full | Antiphospholipid Syndrome |
| title_fullStr | Antiphospholipid Syndrome |
| title_full_unstemmed | Antiphospholipid Syndrome |
| title_short | Antiphospholipid Syndrome |
| title_sort | antiphospholipid syndrome |
| topic | Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology |
| topic_facet | Haematology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJF Haematology |
| url | ONIX_20220727_9781839690549_172 |