RNA, the Epicenter of Genetic Information
The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature...
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| Main Authors: | , |
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| 格式: | Online |
| 語言: | 英语 |
| 出版: |
Taylor & Francis
2022
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| 主題: | |
| 在線閱讀: | ONIX_20220722_9781000623086_18 |
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沒有標簽, 成為第一個標記此記錄!
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| _version_ | 1869526359840129024 |
|---|---|
| author | Mattick, John Amaral, Paulo |
| author_browse | Amaral, Paulo Mattick, John |
| author_facet | Mattick, John Amaral, Paulo |
| author_sort | Mattick, John |
| collection | Directory of Open Access Books |
| description | The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. |
| format | Online |
| id | doab-20.500.12854ir-90454 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Taylor & Francis |
| publisherStr | Taylor & Francis |
| record_format | ojs |
| spelling | doab-20.500.12854ir-904542025-07-30T11:55:44Z RNA, the Epicenter of Genetic Information Mattick, John Amaral, Paulo Cloning Double Helix Genetic Code Genetic Engineering Gene Regulation Genome Structure and Function thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. 2022-08-03T04:01:52Z 2022-08-03T04:01:52Z 2022-07-22T12:07:10Z 2023 book ONIX_20220722_9781000623086_18 OCN: 1295618543 https://library.oapen.org/handle/20.500.12657/57585 9781000623086 9781003109242 9780367623920 9780367567781 https://directory.doabooks.org/handle/20.500.12854/90454 eng open access image/jpeg image/jpeg image/jpeg n/a n/a n/a https://library.oapen.org/bitstream/20.500.12657/57585/1/9781000623086.pdf https://library.oapen.org/bitstream/20.500.12657/57585/1/9781000623086.pdf https://library.oapen.org/bitstream/20.500.12657/57585/1/9781000623086.pdf Taylor & Francis CRC Press 10.1201/9781003109242 10.1201/9781003109242 fa69b019-f4ee-4979-8d42-c6b6c476b5f0 9781000623086 9781003109242 9780367623920 9780367567781 CRC Press 400 open access |
| spellingShingle | Cloning Double Helix Genetic Code Genetic Engineering Gene Regulation Genome Structure and Function thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics Mattick, John Amaral, Paulo RNA, the Epicenter of Genetic Information |
| title | RNA, the Epicenter of Genetic Information |
| title_full | RNA, the Epicenter of Genetic Information |
| title_fullStr | RNA, the Epicenter of Genetic Information |
| title_full_unstemmed | RNA, the Epicenter of Genetic Information |
| title_short | RNA, the Epicenter of Genetic Information |
| title_sort | rna the epicenter of genetic information |
| topic | Cloning Double Helix Genetic Code Genetic Engineering Gene Regulation Genome Structure and Function thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics |
| topic_facet | Cloning Double Helix Genetic Code Genetic Engineering Gene Regulation Genome Structure and Function thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysics |
| url | ONIX_20220722_9781000623086_18 |
| work_keys_str_mv | AT mattickjohn rnatheepicenterofgeneticinformation AT amaralpaulo rnatheepicenterofgeneticinformation |