Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing

This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The ident...

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collection Directory of Open Access Books
description This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents.
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id doab-20.500.12854ir-91208
institution Directory of Open Access Books
language eng
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-912082024-03-28T03:33:45Z Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing Kim, Jong Heon Cheng, Luisa W. Land, Kirkwood nanoparticles fungi drug delivery systems marine biological synthesis myconanotechnology canesten clotrimazole vulvovaginal vaginitis mycosis candidosis yeast infection candida candida albicans vaginal health anticandidal activity indazole pyrazole 3-phenyl-1H-indazole drug design acetylsalicylic acid (ASA, aspirin) capsule CAP64 Cryptococcus membrane potential (ΔΨM) photodynamic treatment photosensitiser ultrastructure drug repurposing antifungals repositioning yeasts emerging fungi multidrug resistance therapeutic alternatives new targets Candida auris Aspergillus spp. antifungal beta-glucan polycations Galleria mellonella model retinoids Candida spp. onychomycosis Malassezia spp. dermatophytes microbiology mycology all-trans retinoic acid Acanthamoeba free-living ameba Acanthamoeba keratitis isavuconazonium sulfate cyst drug drug discovery drug targets invasive aspergillosis treatment invasive fungal infections fission yeast cell wall β(1,3)-D-glucan synthase antifungal drugs echinocandin drugs echinocandin resistance Fks resistance hot spots cytokinesis septation cell separation cell integrity cell lysis sporotrichosis Felis catus quinones hydrazones zoonoses host-directed drug therapy azoles polyenes echinocandins viral infections azole synergy resistance Candida natural products n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents. 2022-08-12T12:51:00Z 2022-08-12T12:51:00Z 2022 book ONIX_20220812_9783036547688_87 9783036547688 9783036547671 https://directory.doabooks.org/handle/20.500.12854/91208 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5854 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4767-1 10.3390/books978-3-0365-4767-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036547688 9783036547671 282 Basel open access
spellingShingle nanoparticles
fungi
drug delivery systems
marine
biological synthesis
myconanotechnology
canesten
clotrimazole
vulvovaginal
vaginitis
mycosis
candidosis
yeast infection
candida
candida albicans
vaginal health
anticandidal activity
indazole
pyrazole
3-phenyl-1H-indazole
drug design
acetylsalicylic acid (ASA, aspirin)
capsule
CAP64
Cryptococcus
membrane potential (ΔΨM)
photodynamic treatment
photosensitiser
ultrastructure
drug repurposing
antifungals
repositioning
yeasts
emerging fungi
multidrug resistance
therapeutic alternatives
new targets
Candida auris
Aspergillus spp.
antifungal
beta-glucan
polycations
Galleria mellonella model
retinoids
Candida spp.
onychomycosis
Malassezia spp.
dermatophytes
microbiology
mycology
all-trans retinoic acid
Acanthamoeba
free-living ameba
Acanthamoeba keratitis
isavuconazonium sulfate
cyst
drug
drug discovery
drug targets
invasive aspergillosis treatment
invasive fungal infections
fission yeast
cell wall
β(1,3)-D-glucan synthase
antifungal drugs
echinocandin drugs
echinocandin resistance
Fks resistance hot spots
cytokinesis
septation
cell separation
cell integrity
cell lysis
sporotrichosis
Felis catus
quinones
hydrazones
zoonoses
host-directed drug therapy
azoles
polyenes
echinocandins
viral infections
azole
synergy
resistance
Candida
natural products
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
title Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
title_full Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
title_fullStr Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
title_full_unstemmed Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
title_short Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
title_sort advances in antifungal development discovery of new drugs and drug repurposing
topic nanoparticles
fungi
drug delivery systems
marine
biological synthesis
myconanotechnology
canesten
clotrimazole
vulvovaginal
vaginitis
mycosis
candidosis
yeast infection
candida
candida albicans
vaginal health
anticandidal activity
indazole
pyrazole
3-phenyl-1H-indazole
drug design
acetylsalicylic acid (ASA, aspirin)
capsule
CAP64
Cryptococcus
membrane potential (ΔΨM)
photodynamic treatment
photosensitiser
ultrastructure
drug repurposing
antifungals
repositioning
yeasts
emerging fungi
multidrug resistance
therapeutic alternatives
new targets
Candida auris
Aspergillus spp.
antifungal
beta-glucan
polycations
Galleria mellonella model
retinoids
Candida spp.
onychomycosis
Malassezia spp.
dermatophytes
microbiology
mycology
all-trans retinoic acid
Acanthamoeba
free-living ameba
Acanthamoeba keratitis
isavuconazonium sulfate
cyst
drug
drug discovery
drug targets
invasive aspergillosis treatment
invasive fungal infections
fission yeast
cell wall
β(1,3)-D-glucan synthase
antifungal drugs
echinocandin drugs
echinocandin resistance
Fks resistance hot spots
cytokinesis
septation
cell separation
cell integrity
cell lysis
sporotrichosis
Felis catus
quinones
hydrazones
zoonoses
host-directed drug therapy
azoles
polyenes
echinocandins
viral infections
azole
synergy
resistance
Candida
natural products
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet nanoparticles
fungi
drug delivery systems
marine
biological synthesis
myconanotechnology
canesten
clotrimazole
vulvovaginal
vaginitis
mycosis
candidosis
yeast infection
candida
candida albicans
vaginal health
anticandidal activity
indazole
pyrazole
3-phenyl-1H-indazole
drug design
acetylsalicylic acid (ASA, aspirin)
capsule
CAP64
Cryptococcus
membrane potential (ΔΨM)
photodynamic treatment
photosensitiser
ultrastructure
drug repurposing
antifungals
repositioning
yeasts
emerging fungi
multidrug resistance
therapeutic alternatives
new targets
Candida auris
Aspergillus spp.
antifungal
beta-glucan
polycations
Galleria mellonella model
retinoids
Candida spp.
onychomycosis
Malassezia spp.
dermatophytes
microbiology
mycology
all-trans retinoic acid
Acanthamoeba
free-living ameba
Acanthamoeba keratitis
isavuconazonium sulfate
cyst
drug
drug discovery
drug targets
invasive aspergillosis treatment
invasive fungal infections
fission yeast
cell wall
β(1,3)-D-glucan synthase
antifungal drugs
echinocandin drugs
echinocandin resistance
Fks resistance hot spots
cytokinesis
septation
cell separation
cell integrity
cell lysis
sporotrichosis
Felis catus
quinones
hydrazones
zoonoses
host-directed drug therapy
azoles
polyenes
echinocandins
viral infections
azole
synergy
resistance
Candida
natural products
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20220812_9783036547688_87