Intraocular Pressure and Ocular Hypertension
Primary open-angle glaucoma (POAG) is a multi-factorial progressive optic neuropathy characterized by retinal ganglion cell degeneration and progressive visual field loss which, if left untreated, may lead to blindness. Increased intraocular pressure (IOP) is considered to be the main risk factor fo...
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2022
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| Sarrera elektronikoa: | ONIX_20220916_9783036551005_122 |
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| description | Primary open-angle glaucoma (POAG) is a multi-factorial progressive optic neuropathy characterized by retinal ganglion cell degeneration and progressive visual field loss which, if left untreated, may lead to blindness. Increased intraocular pressure (IOP) is considered to be the main risk factor for developing POAG, and its reduction has been shown to correlate with a decrease in glaucoma incidence and progression. Considering that fewer than 10% of the subjects with ocular hypertension (OHT) will develop morphological and/or functional glaucomatous damage within 5 years if not treated, glaucoma causes and molecular changes leading to ocular tissue damage in glaucoma are still largely unknown. The contemporary treatment of POAG is mainly oriented towards reducing IOP; the importance of the IOP reduction in other types of glaucoma, such as the “normal pressure glaucoma”, is still discussed. The IOP value is maintained by balancing the amount of fluid contained within the anterior and posterior chambers of the eye; our comprehension of the mechanisms underlying the secretion and active and passive outflow of the aqueous humor is extremely important for improving the treatment of glaucoma. Innovative pharmacological approaches, and laser and surgical procedures aiming to reduce IOP, have been developed in recent years. This book provides a compendium of topics regarding IOP, aqueous humor dynamics, tonometry, and medical and surgical techniques developed to reduce the IOP in subjects with ocular hypertension or glaucoma. |
| format | Online |
| id | doab-20.500.12854ir-92136 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
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| spelling | doab-20.500.12854ir-921362024-03-30T23:22:31Z Intraocular Pressure and Ocular Hypertension Brusini, Paolo Salvetat, Maria Letizia Zeppieri, Marco intraocular pressure serum calcium female ab interno trabeculotomy glaucoma incision in the Schlemm’s canal in degrees post-surgical complication neuroretinal rim reversal Bruch’s membrane opening-minimum rim width trabeculectomy refractive error neuroretina myopia intraocular pressure (IOP) tonometry Goldmann applanation tonometer (GAT) central corneal thickness (CCT) ocular hypertension higher-order aberrations Kahook Dual Blade age central corneal thickness Goldmann Applanation tonometer non-contact tonometer rebound tonometer iCare open angle glaucoma (OAG) Schlemm’s canal viscodilation OMNI viscosurgical system minimally invasive glaucoma surgeries (MIGS) trabeculotomy cataract extraction aqueous humor GDF15 serum intravitreal injection anti-VEGF agents trabecular meshwork Matrigel 3D culture outflow cytoskeleton rho-kinase inhibitor prostaglandin analog childhood glaucoma aphakia pseudophakia cataract surgery lensectomy management (or therapy) glaucoma drainage device cyclodestruction corneal biomechanics ocular response analyzer ORA corneal hysteresis non-penetrating deep sclerectomy Esnoper V-2000 implant glucocorticoids safety profile intranasal administration inhaled administration systemic administration steroid response canaloplasty non-perforating surgical procedures pseudoexfoliation glaucoma (PEXG) Schlemm’s canal phase-sensitive optical coherent tomography pulsatile motion IOP fluctuation primary open-angle glaucoma intraocular pressure measurement iCare tonometry Perkins tonometry standardized anaesthesia corneal thickness progression risk stratification XEN GelStent corneal resistance factor open-angle glaucoma n/a laser treatment dropless treatment thyroid-associated ophthalmopathy extraocular muscle magnetic resonance imaging T2 relaxation time thema EDItEUR::M Medicine and Nursing Primary open-angle glaucoma (POAG) is a multi-factorial progressive optic neuropathy characterized by retinal ganglion cell degeneration and progressive visual field loss which, if left untreated, may lead to blindness. Increased intraocular pressure (IOP) is considered to be the main risk factor for developing POAG, and its reduction has been shown to correlate with a decrease in glaucoma incidence and progression. Considering that fewer than 10% of the subjects with ocular hypertension (OHT) will develop morphological and/or functional glaucomatous damage within 5 years if not treated, glaucoma causes and molecular changes leading to ocular tissue damage in glaucoma are still largely unknown. The contemporary treatment of POAG is mainly oriented towards reducing IOP; the importance of the IOP reduction in other types of glaucoma, such as the “normal pressure glaucoma”, is still discussed. The IOP value is maintained by balancing the amount of fluid contained within the anterior and posterior chambers of the eye; our comprehension of the mechanisms underlying the secretion and active and passive outflow of the aqueous humor is extremely important for improving the treatment of glaucoma. Innovative pharmacological approaches, and laser and surgical procedures aiming to reduce IOP, have been developed in recent years. This book provides a compendium of topics regarding IOP, aqueous humor dynamics, tonometry, and medical and surgical techniques developed to reduce the IOP in subjects with ocular hypertension or glaucoma. 2022-09-16T13:48:06Z 2022-09-16T13:48:06Z 2022 book ONIX_20220916_9783036551005_122 9783036551005 9783036550992 https://directory.doabooks.org/handle/20.500.12854/92136 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6013 https://mdpi.com/books/pdfview/book/6013 10.3390/books978-3-0365-5099-2 10.3390/books978-3-0365-5099-2 MDPI - Multidisciplinary Digital Publishing Institute 9783036551005 9783036550992 288 Basel open access |
| spellingShingle | intraocular pressure serum calcium female ab interno trabeculotomy glaucoma incision in the Schlemm’s canal in degrees post-surgical complication neuroretinal rim reversal Bruch’s membrane opening-minimum rim width trabeculectomy refractive error neuroretina myopia intraocular pressure (IOP) tonometry Goldmann applanation tonometer (GAT) central corneal thickness (CCT) ocular hypertension higher-order aberrations Kahook Dual Blade age central corneal thickness Goldmann Applanation tonometer non-contact tonometer rebound tonometer iCare open angle glaucoma (OAG) Schlemm’s canal viscodilation OMNI viscosurgical system minimally invasive glaucoma surgeries (MIGS) trabeculotomy cataract extraction aqueous humor GDF15 serum intravitreal injection anti-VEGF agents trabecular meshwork Matrigel 3D culture outflow cytoskeleton rho-kinase inhibitor prostaglandin analog childhood glaucoma aphakia pseudophakia cataract surgery lensectomy management (or therapy) glaucoma drainage device cyclodestruction corneal biomechanics ocular response analyzer ORA corneal hysteresis non-penetrating deep sclerectomy Esnoper V-2000 implant glucocorticoids safety profile intranasal administration inhaled administration systemic administration steroid response canaloplasty non-perforating surgical procedures pseudoexfoliation glaucoma (PEXG) Schlemm’s canal phase-sensitive optical coherent tomography pulsatile motion IOP fluctuation primary open-angle glaucoma intraocular pressure measurement iCare tonometry Perkins tonometry standardized anaesthesia corneal thickness progression risk stratification XEN GelStent corneal resistance factor open-angle glaucoma n/a laser treatment dropless treatment thyroid-associated ophthalmopathy extraocular muscle magnetic resonance imaging T2 relaxation time thema EDItEUR::M Medicine and Nursing Intraocular Pressure and Ocular Hypertension |
| title | Intraocular Pressure and Ocular Hypertension |
| title_full | Intraocular Pressure and Ocular Hypertension |
| title_fullStr | Intraocular Pressure and Ocular Hypertension |
| title_full_unstemmed | Intraocular Pressure and Ocular Hypertension |
| title_short | Intraocular Pressure and Ocular Hypertension |
| title_sort | intraocular pressure and ocular hypertension |
| topic | intraocular pressure serum calcium female ab interno trabeculotomy glaucoma incision in the Schlemm’s canal in degrees post-surgical complication neuroretinal rim reversal Bruch’s membrane opening-minimum rim width trabeculectomy refractive error neuroretina myopia intraocular pressure (IOP) tonometry Goldmann applanation tonometer (GAT) central corneal thickness (CCT) ocular hypertension higher-order aberrations Kahook Dual Blade age central corneal thickness Goldmann Applanation tonometer non-contact tonometer rebound tonometer iCare open angle glaucoma (OAG) Schlemm’s canal viscodilation OMNI viscosurgical system minimally invasive glaucoma surgeries (MIGS) trabeculotomy cataract extraction aqueous humor GDF15 serum intravitreal injection anti-VEGF agents trabecular meshwork Matrigel 3D culture outflow cytoskeleton rho-kinase inhibitor prostaglandin analog childhood glaucoma aphakia pseudophakia cataract surgery lensectomy management (or therapy) glaucoma drainage device cyclodestruction corneal biomechanics ocular response analyzer ORA corneal hysteresis non-penetrating deep sclerectomy Esnoper V-2000 implant glucocorticoids safety profile intranasal administration inhaled administration systemic administration steroid response canaloplasty non-perforating surgical procedures pseudoexfoliation glaucoma (PEXG) Schlemm’s canal phase-sensitive optical coherent tomography pulsatile motion IOP fluctuation primary open-angle glaucoma intraocular pressure measurement iCare tonometry Perkins tonometry standardized anaesthesia corneal thickness progression risk stratification XEN GelStent corneal resistance factor open-angle glaucoma n/a laser treatment dropless treatment thyroid-associated ophthalmopathy extraocular muscle magnetic resonance imaging T2 relaxation time thema EDItEUR::M Medicine and Nursing |
| topic_facet | intraocular pressure serum calcium female ab interno trabeculotomy glaucoma incision in the Schlemm’s canal in degrees post-surgical complication neuroretinal rim reversal Bruch’s membrane opening-minimum rim width trabeculectomy refractive error neuroretina myopia intraocular pressure (IOP) tonometry Goldmann applanation tonometer (GAT) central corneal thickness (CCT) ocular hypertension higher-order aberrations Kahook Dual Blade age central corneal thickness Goldmann Applanation tonometer non-contact tonometer rebound tonometer iCare open angle glaucoma (OAG) Schlemm’s canal viscodilation OMNI viscosurgical system minimally invasive glaucoma surgeries (MIGS) trabeculotomy cataract extraction aqueous humor GDF15 serum intravitreal injection anti-VEGF agents trabecular meshwork Matrigel 3D culture outflow cytoskeleton rho-kinase inhibitor prostaglandin analog childhood glaucoma aphakia pseudophakia cataract surgery lensectomy management (or therapy) glaucoma drainage device cyclodestruction corneal biomechanics ocular response analyzer ORA corneal hysteresis non-penetrating deep sclerectomy Esnoper V-2000 implant glucocorticoids safety profile intranasal administration inhaled administration systemic administration steroid response canaloplasty non-perforating surgical procedures pseudoexfoliation glaucoma (PEXG) Schlemm’s canal phase-sensitive optical coherent tomography pulsatile motion IOP fluctuation primary open-angle glaucoma intraocular pressure measurement iCare tonometry Perkins tonometry standardized anaesthesia corneal thickness progression risk stratification XEN GelStent corneal resistance factor open-angle glaucoma n/a laser treatment dropless treatment thyroid-associated ophthalmopathy extraocular muscle magnetic resonance imaging T2 relaxation time thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220916_9783036551005_122 |