Gastrointestinal Cancers
Gastrointestinal cancers represent a heterogeneous group of diseases of the gastrointestinal tract. There is an interplay of various non-modifiable and modifiable risk factors that foster the conversion of normal cells to precursor cells, precursor cells to premalignant cells, and premalignant cells...
Tallennettuna:
| Aineistotyyppi: | Online |
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| Kieli: | englanti |
| Julkaistu: |
Exon Publications
2022
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| Aiheet: | |
| Linkit: | https://directory.doabooks.org/handle/20.500.12854/92984 |
| Tagit: |
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| _version_ | 1869531286990749696 |
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| collection | Directory of Open Access Books |
| description | Gastrointestinal cancers represent a heterogeneous group of diseases of the gastrointestinal tract. There is an interplay of various non-modifiable and modifiable risk factors that foster the conversion of normal cells to precursor cells, precursor cells to premalignant cells, and premalignant cells to malignant cells. Gastrointestinal cancers are diverse in etiology and clinical management. The chapters of this book explore the clinically relevant aspects of this diversity under three broad categories: epidemiology and pathology, early diagnosis and prognosis, and surgical management. The etiological aspects focus on stomach cancer while the pathological aspects provide an overview of colorectal cancer, how primary colorectal cancer becomes metastatic through epithelial mesenchymal transition, and how macrophage-derived extracellular vesicles drive tumor development and enable the progression of most gastrointestinal cancers. Chapters on early detection and prognosis emphasize on biomarker discovery, both at genetic and proteomic level, and how these can be used to effectively predict the origin, progress, prognosis, and treatment response of gastrointestinal cancers in general and pancreatic cancer in particular. Given that the gastrointestinal tract is solely responsible for the processing of the diet we consume, the impact of diet that we consume cannot be ignored. There is a dedicated chapter that covers the role of diet and lifestyle on colorectal cancer incidence and survival. Despite various treatment modalities, for localized cancers, surgery is still the best form of curative treatment, and the role of surgical management of gastrointestinal stromal tumors and esophageal cancers are elegantly summarized in two chapters. The contents of this book provide the readers with an overview of several important aspects of gastrointestinal cancers and may be of interest to healthcare professionals interested in gastrointestinal cancers. |
| format | Online |
| id | doab-20.500.12854ir-92984 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Exon Publications |
| publisherStr | Exon Publications |
| record_format | ojs |
| spelling | doab-20.500.12854ir-929842022-10-21T06:43:06Z Gastrointestinal Cancers Morgado-Diaz, Jose Andres gastrointestinal cancers stomach cancer pancreatic cancer colorectal cancer gastrointestinal stromal tumors esophageal cancer MJCL Gastrointestinal cancers represent a heterogeneous group of diseases of the gastrointestinal tract. There is an interplay of various non-modifiable and modifiable risk factors that foster the conversion of normal cells to precursor cells, precursor cells to premalignant cells, and premalignant cells to malignant cells. Gastrointestinal cancers are diverse in etiology and clinical management. The chapters of this book explore the clinically relevant aspects of this diversity under three broad categories: epidemiology and pathology, early diagnosis and prognosis, and surgical management. The etiological aspects focus on stomach cancer while the pathological aspects provide an overview of colorectal cancer, how primary colorectal cancer becomes metastatic through epithelial mesenchymal transition, and how macrophage-derived extracellular vesicles drive tumor development and enable the progression of most gastrointestinal cancers. Chapters on early detection and prognosis emphasize on biomarker discovery, both at genetic and proteomic level, and how these can be used to effectively predict the origin, progress, prognosis, and treatment response of gastrointestinal cancers in general and pancreatic cancer in particular. Given that the gastrointestinal tract is solely responsible for the processing of the diet we consume, the impact of diet that we consume cannot be ignored. There is a dedicated chapter that covers the role of diet and lifestyle on colorectal cancer incidence and survival. Despite various treatment modalities, for localized cancers, surgery is still the best form of curative treatment, and the role of surgical management of gastrointestinal stromal tumors and esophageal cancers are elegantly summarized in two chapters. The contents of this book provide the readers with an overview of several important aspects of gastrointestinal cancers and may be of interest to healthcare professionals interested in gastrointestinal cancers. Published 2022-10-21T06:43:05Z 2022-10-21T06:43:05Z 2022-09-30 book 978-0-6453320-6-3 https://directory.doabooks.org/handle/20.500.12854/92984 eng image/png Attribution-NonCommercial-NoDerivatives 4.0 International https://exonpublications.com/index.php/exon/issue/view/gastrointestinal-cancers-open-access-book Exon Publications Electronic 10.36255/exon-publications-gastrointestinal-cancers 10.36255/exon-publications-gastrointestinal-cancers 2d6001a3-9e06-4979-bf02-6974e313eb24 978-0-6453320-6-3 Electronic Brisbane, Australia open access |
| spellingShingle | gastrointestinal cancers stomach cancer pancreatic cancer colorectal cancer gastrointestinal stromal tumors esophageal cancer MJCL Gastrointestinal Cancers |
| title | Gastrointestinal Cancers |
| title_full | Gastrointestinal Cancers |
| title_fullStr | Gastrointestinal Cancers |
| title_full_unstemmed | Gastrointestinal Cancers |
| title_short | Gastrointestinal Cancers |
| title_sort | gastrointestinal cancers |
| topic | gastrointestinal cancers stomach cancer pancreatic cancer colorectal cancer gastrointestinal stromal tumors esophageal cancer MJCL |
| topic_facet | gastrointestinal cancers stomach cancer pancreatic cancer colorectal cancer gastrointestinal stromal tumors esophageal cancer MJCL |
| url | https://directory.doabooks.org/handle/20.500.12854/92984 |