Nanoparticle-Macrophage Interactions
Nanoparticles (NPs) offer unique properties for biomedical applications, leading to new nanomedicines. Recent examples of advanced nanoparticle-based nanomedicines are COVID-19 RNA vaccines. Regardless of the delivery route of the NPs into the body (intravenous or subcutaneous injection, oral, intra...
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| Format: | Online |
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| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Teme: | |
| Online pristup: | ONIX_20221025_9783036545998_28 |
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Bez oznaka, Budi prvi tko označuje ovaj zapis!
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| _version_ | 1869530909596712960 |
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| collection | Directory of Open Access Books |
| description | Nanoparticles (NPs) offer unique properties for biomedical applications, leading to new nanomedicines. Recent examples of advanced nanoparticle-based nanomedicines are COVID-19 RNA vaccines. Regardless of the delivery route of the NPs into the body (intravenous or subcutaneous injection, oral, intranasal, etc.), NPs inevitably come into contact with immune cells, such as macrophages. Macrophages are phagocytizing cells that determine the fate and the lifetime of NPs in relevant biological fluids or tissues, which has consequences for both nanosafety and nanomedicine. The aim of this Special Issue is to cover recent advancements in our understanding of NP–macrophage interactions, with a focus on in vitro models for nanosafety and novel nanomedicine approaches that allow the modulation of the immunological profile of macrophages. The current Special Issue compiles nine papers: seven research articles and two review articles. The original articles include studies on the interaction of different nanomaterials, such as multi-walled carbon nanotubes (MWCNTs), amorphous silica, gold nanoparticles, lipid carriers, and microspheres, with macrophages in different scenarios. |
| format | Online |
| id | doab-20.500.12854ir-93174 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-931742024-03-31T13:10:16Z Nanoparticle-Macrophage Interactions Bondarenko, Olesja Torres Andón, Fernando chronic wound device foot ulcer inflammation wound healing macrophage nanomaterial nanoparticle drug delivery immune system anti-inflammatory innate immunity osteoarthritis rifabutin nanostructured lipid carriers cell uptake Caco-2 cells oral administration Crohn’s disease nanomaterials macrophages class A type 1 scavenger receptors cytotoxicity macrophage–nanoparticle interaction monocytes gold nanoparticles in vitro models innate memory 2D cultures 3D cultures carbon nanotube scavenger receptor phagocytosis protein corona bovine serum albumin synthetic amorphous silica in vitro testing NR8383 alveolar macrophage ICP-MS analysis of cell bound SiO2 multi-walled carbon nanotubes nanoparticles chemokines transcriptomics zebrafish n/a thema EDItEUR::M Medicine and Nursing Nanoparticles (NPs) offer unique properties for biomedical applications, leading to new nanomedicines. Recent examples of advanced nanoparticle-based nanomedicines are COVID-19 RNA vaccines. Regardless of the delivery route of the NPs into the body (intravenous or subcutaneous injection, oral, intranasal, etc.), NPs inevitably come into contact with immune cells, such as macrophages. Macrophages are phagocytizing cells that determine the fate and the lifetime of NPs in relevant biological fluids or tissues, which has consequences for both nanosafety and nanomedicine. The aim of this Special Issue is to cover recent advancements in our understanding of NP–macrophage interactions, with a focus on in vitro models for nanosafety and novel nanomedicine approaches that allow the modulation of the immunological profile of macrophages. The current Special Issue compiles nine papers: seven research articles and two review articles. The original articles include studies on the interaction of different nanomaterials, such as multi-walled carbon nanotubes (MWCNTs), amorphous silica, gold nanoparticles, lipid carriers, and microspheres, with macrophages in different scenarios. 2022-10-25T09:00:28Z 2022-10-25T09:00:28Z 2022 book ONIX_20221025_9783036545998_28 9783036545998 9783036546001 https://directory.doabooks.org/handle/20.500.12854/93174 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6070 https://mdpi.com/books/pdfview/book/6070 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4600-1 10.3390/books978-3-0365-4600-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036545998 9783036546001 208 open access |
| spellingShingle | chronic wound device foot ulcer inflammation wound healing macrophage nanomaterial nanoparticle drug delivery immune system anti-inflammatory innate immunity osteoarthritis rifabutin nanostructured lipid carriers cell uptake Caco-2 cells oral administration Crohn’s disease nanomaterials macrophages class A type 1 scavenger receptors cytotoxicity macrophage–nanoparticle interaction monocytes gold nanoparticles in vitro models innate memory 2D cultures 3D cultures carbon nanotube scavenger receptor phagocytosis protein corona bovine serum albumin synthetic amorphous silica in vitro testing NR8383 alveolar macrophage ICP-MS analysis of cell bound SiO2 multi-walled carbon nanotubes nanoparticles chemokines transcriptomics zebrafish n/a thema EDItEUR::M Medicine and Nursing Nanoparticle-Macrophage Interactions |
| title | Nanoparticle-Macrophage Interactions |
| title_full | Nanoparticle-Macrophage Interactions |
| title_fullStr | Nanoparticle-Macrophage Interactions |
| title_full_unstemmed | Nanoparticle-Macrophage Interactions |
| title_short | Nanoparticle-Macrophage Interactions |
| title_sort | nanoparticle macrophage interactions |
| topic | chronic wound device foot ulcer inflammation wound healing macrophage nanomaterial nanoparticle drug delivery immune system anti-inflammatory innate immunity osteoarthritis rifabutin nanostructured lipid carriers cell uptake Caco-2 cells oral administration Crohn’s disease nanomaterials macrophages class A type 1 scavenger receptors cytotoxicity macrophage–nanoparticle interaction monocytes gold nanoparticles in vitro models innate memory 2D cultures 3D cultures carbon nanotube scavenger receptor phagocytosis protein corona bovine serum albumin synthetic amorphous silica in vitro testing NR8383 alveolar macrophage ICP-MS analysis of cell bound SiO2 multi-walled carbon nanotubes nanoparticles chemokines transcriptomics zebrafish n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | chronic wound device foot ulcer inflammation wound healing macrophage nanomaterial nanoparticle drug delivery immune system anti-inflammatory innate immunity osteoarthritis rifabutin nanostructured lipid carriers cell uptake Caco-2 cells oral administration Crohn’s disease nanomaterials macrophages class A type 1 scavenger receptors cytotoxicity macrophage–nanoparticle interaction monocytes gold nanoparticles in vitro models innate memory 2D cultures 3D cultures carbon nanotube scavenger receptor phagocytosis protein corona bovine serum albumin synthetic amorphous silica in vitro testing NR8383 alveolar macrophage ICP-MS analysis of cell bound SiO2 multi-walled carbon nanotubes nanoparticles chemokines transcriptomics zebrafish n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20221025_9783036545998_28 |