Pig Genomics and Genetics
In this Special Issue, we present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances. The published manuscripts focused on...
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| Materyal Türü: | Online |
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| Dil: | İngilizce |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Konular: | |
| Online Erişim: | ONIX_20221025_9783036553580_80 |
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| _version_ | 1869518952376303616 |
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| collection | Directory of Open Access Books |
| description | In this Special Issue, we present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances. The published manuscripts focused on high-throughput methodologies, such as RNA sequencing, ATAC-seq, MACE-seq, chip-seq, and RRBS, and covered other fields of pig genetics. The pig (Sus scrofa) is the most common large mammal in the world. The Sus genus includes domestic pig and wild boar. Since the draft reference genome sequence of S. scrofa was assembled in 2012, the processes of identification of genes related to important phenotypic traits and of search of genetic markers for pig selection have been significantly refined. In addition, the newest wide-range high-throughput techniques, including microarrays, next-generation sequencing, and the recent PacBio sequencing platform providing ultra-long sequencing reads, allow identifying gene mutations and gene candidates throughout the whole genome, transcriptome, or epigenome and estimating quantitative traits important for breeding as well as the genetic backgrounds of inherited diseases. |
| format | Online |
| id | doab-20.500.12854ir-93226 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-932262024-03-28T03:31:17Z Pig Genomics and Genetics Piórkowska, Katarzyna Ropka-Molik, Katarzyna HMOX1 gene promoter transcriptional regulation Hezuo Tibetan pig AQP3 pig intramuscular fat adipogenesis proliferation litter size total number born alive SNP (single nucleotide polymorphism) GWAS (Genome-Wide Association Studies) heat stress Duroc RNA-Seq NMR metabolome fatness obesity extracellular matrix fat deposition lipid metabolism NGS genetically modified pigs genome modifications transgenic pigs genetic engineering disease models recombinant proteins xenotransplantation xenoantigen coagulation system dysregulation CRISPR/Cas9 system non-homologous DNA ends joining (NHEJ) TIDE analysis off-target skeletal muscle fiber meat quality metabolic diseases lncRNA RNA-seq porcine β-defensin 2 CRISPR/Cas9 antimicrobial peptide disease-resistant animals porcine alveolar macrophages DNMT3B DNA methylation isoform TNF-α pigs fatty acids 3′quant mRNA-seq nutrigenomics TRIM26 antiviral response IFN-β poly (I:C) VSV PRRSV seminal plasma endometrium global gene expression microarray alternative splicing transcript protein domain single nucleotide polymorphism hypothalamus puberty circRNAs pubertal genes Duroc pigs growth traits weighted single-step GWAS SNP gene expression congenital defects transcriptomics swine Sus scrofa precision medicine lymphatic system whole-genome sequencing SNP array genotyping n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences In this Special Issue, we present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances. The published manuscripts focused on high-throughput methodologies, such as RNA sequencing, ATAC-seq, MACE-seq, chip-seq, and RRBS, and covered other fields of pig genetics. The pig (Sus scrofa) is the most common large mammal in the world. The Sus genus includes domestic pig and wild boar. Since the draft reference genome sequence of S. scrofa was assembled in 2012, the processes of identification of genes related to important phenotypic traits and of search of genetic markers for pig selection have been significantly refined. In addition, the newest wide-range high-throughput techniques, including microarrays, next-generation sequencing, and the recent PacBio sequencing platform providing ultra-long sequencing reads, allow identifying gene mutations and gene candidates throughout the whole genome, transcriptome, or epigenome and estimating quantitative traits important for breeding as well as the genetic backgrounds of inherited diseases. 2022-10-25T09:02:56Z 2022-10-25T09:02:56Z 2022 book ONIX_20221025_9783036553580_80 9783036553580 9783036553573 https://directory.doabooks.org/handle/20.500.12854/93226 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6124 https://mdpi.com/books/pdfview/book/6124 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5357-3 10.3390/books978-3-0365-5357-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036553580 9783036553573 318 open access |
| spellingShingle | HMOX1 gene promoter transcriptional regulation Hezuo Tibetan pig AQP3 pig intramuscular fat adipogenesis proliferation litter size total number born alive SNP (single nucleotide polymorphism) GWAS (Genome-Wide Association Studies) heat stress Duroc RNA-Seq NMR metabolome fatness obesity extracellular matrix fat deposition lipid metabolism NGS genetically modified pigs genome modifications transgenic pigs genetic engineering disease models recombinant proteins xenotransplantation xenoantigen coagulation system dysregulation CRISPR/Cas9 system non-homologous DNA ends joining (NHEJ) TIDE analysis off-target skeletal muscle fiber meat quality metabolic diseases lncRNA RNA-seq porcine β-defensin 2 CRISPR/Cas9 antimicrobial peptide disease-resistant animals porcine alveolar macrophages DNMT3B DNA methylation isoform TNF-α pigs fatty acids 3′quant mRNA-seq nutrigenomics TRIM26 antiviral response IFN-β poly (I:C) VSV PRRSV seminal plasma endometrium global gene expression microarray alternative splicing transcript protein domain single nucleotide polymorphism hypothalamus puberty circRNAs pubertal genes Duroc pigs growth traits weighted single-step GWAS SNP gene expression congenital defects transcriptomics swine Sus scrofa precision medicine lymphatic system whole-genome sequencing SNP array genotyping n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences Pig Genomics and Genetics |
| title | Pig Genomics and Genetics |
| title_full | Pig Genomics and Genetics |
| title_fullStr | Pig Genomics and Genetics |
| title_full_unstemmed | Pig Genomics and Genetics |
| title_short | Pig Genomics and Genetics |
| title_sort | pig genomics and genetics |
| topic | HMOX1 gene promoter transcriptional regulation Hezuo Tibetan pig AQP3 pig intramuscular fat adipogenesis proliferation litter size total number born alive SNP (single nucleotide polymorphism) GWAS (Genome-Wide Association Studies) heat stress Duroc RNA-Seq NMR metabolome fatness obesity extracellular matrix fat deposition lipid metabolism NGS genetically modified pigs genome modifications transgenic pigs genetic engineering disease models recombinant proteins xenotransplantation xenoantigen coagulation system dysregulation CRISPR/Cas9 system non-homologous DNA ends joining (NHEJ) TIDE analysis off-target skeletal muscle fiber meat quality metabolic diseases lncRNA RNA-seq porcine β-defensin 2 CRISPR/Cas9 antimicrobial peptide disease-resistant animals porcine alveolar macrophages DNMT3B DNA methylation isoform TNF-α pigs fatty acids 3′quant mRNA-seq nutrigenomics TRIM26 antiviral response IFN-β poly (I:C) VSV PRRSV seminal plasma endometrium global gene expression microarray alternative splicing transcript protein domain single nucleotide polymorphism hypothalamus puberty circRNAs pubertal genes Duroc pigs growth traits weighted single-step GWAS SNP gene expression congenital defects transcriptomics swine Sus scrofa precision medicine lymphatic system whole-genome sequencing SNP array genotyping n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences |
| topic_facet | HMOX1 gene promoter transcriptional regulation Hezuo Tibetan pig AQP3 pig intramuscular fat adipogenesis proliferation litter size total number born alive SNP (single nucleotide polymorphism) GWAS (Genome-Wide Association Studies) heat stress Duroc RNA-Seq NMR metabolome fatness obesity extracellular matrix fat deposition lipid metabolism NGS genetically modified pigs genome modifications transgenic pigs genetic engineering disease models recombinant proteins xenotransplantation xenoantigen coagulation system dysregulation CRISPR/Cas9 system non-homologous DNA ends joining (NHEJ) TIDE analysis off-target skeletal muscle fiber meat quality metabolic diseases lncRNA RNA-seq porcine β-defensin 2 CRISPR/Cas9 antimicrobial peptide disease-resistant animals porcine alveolar macrophages DNMT3B DNA methylation isoform TNF-α pigs fatty acids 3′quant mRNA-seq nutrigenomics TRIM26 antiviral response IFN-β poly (I:C) VSV PRRSV seminal plasma endometrium global gene expression microarray alternative splicing transcript protein domain single nucleotide polymorphism hypothalamus puberty circRNAs pubertal genes Duroc pigs growth traits weighted single-step GWAS SNP gene expression congenital defects transcriptomics swine Sus scrofa precision medicine lymphatic system whole-genome sequencing SNP array genotyping n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences |
| url | ONIX_20221025_9783036553580_80 |