Women in Bioorganic Chemistry
Issues relating to the gender schism and its effect on the career advancement of women in the Academy, especially in the field of STEM disciplines, deserve our attention and the efforts of all the scientific community to mitigate the gender gap. In order to embrace gender equality, recognize the car...
שמור ב:
| פורמט: | Online |
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| שפה: | אנגלית |
| יצא לאור: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| נושאים: | |
| גישה מקוונת: | ONIX_20221025_9783036549897_90 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
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| _version_ | 1869523426192916480 |
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| collection | Directory of Open Access Books |
| description | Issues relating to the gender schism and its effect on the career advancement of women in the Academy, especially in the field of STEM disciplines, deserve our attention and the efforts of all the scientific community to mitigate the gender gap. In order to embrace gender equality, recognize the career progression of women, and to celebrate the achievements of women in the field of bioorganic chemistry, we present contributions both from highly renowned female scientists and young female researchers who are in the early stages of their careers. This Special Issue includes fifteen manuscripts, including eleven high-quality research articles and four comprehensive review articles in the area of bioorganic chemistry, published from mid-2020 to early 2022. The scope of this Special Issue covers a wide range of topics at the organic chemistry–biology interface, including the synthesis and derivatization of natural compounds and their analogues, and the investigation of their biological activities in the human health field (for instance as antitumorals, antioxidants and antimicrobial agents), as well as their possible application in the crop protection field as agrochemicals. An example of nanoparticle-based biomaterial is also included. The techniques employed, besides organic synthesis, are in silico studies (docking procedures and molecular modeling), FT-IR spectroscopy, laser diffraction, PET, fluorescence, STD-NMR studies, enzymatic evaluation, experiments on cell lines and in vivo studies on mice. |
| format | Online |
| id | doab-20.500.12854ir-93236 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-932362024-04-11T15:11:15Z Women in Bioorganic Chemistry Cardona, Francesca Parmeggiani, Camilla Matassini, Camilla antibiotics biochemical studies iminosugars inhibitors insect trehalase trehalose in vivo studies mammalian trehalase natural compounds selectivity interrupted Nazarov cyclization pentacyclic steroids antiproliferative activity d-annulated steroids Lewis acid dental caries enamel remineralisation hydroxyapatite amelogenin amelogenin-derived peptides leucine-rich amelogenin peptides tyrosine-rich amelogenin peptides cannabidiol molecular mechanisms neurological diseases neuroprotective effects strigolactones Strigol anti-cancer antimicrobials sustainable agriculture α,α-difluorophosphonate deoxyxylulose phosphate reductoisomerase 1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR) antimicrobial fosmidomycin isoprenoid biosynthesis 2-C-methyl-derythritol 4-phosphate (MEP) pathway multivalency gold nanoparticles enzyme inhibition Jack bean α-mannosidase aminoproline scaffold integrin targeting ligand design peptidomimetic synthesis leukocyte integrins BODIPY β-galactosidase activity PET fluorescent dispirooxindoles anticancer activity cytotoxicity 3D molecular docking p53/MDM2 interaction terpenes hydrazones penetration enhancers liposomes lipids stratum corneum laser diffraction fluorescence probe pyrene FT-IR spectroscopy heterohelicene chirality resolution enantiomers chiroptical screw-shaped compounds betulinic acid α-glucosidase inhibition mechanism postprandial hyperglycemia synergistic effect AMR persisters (p)ppGpp fragment screening thermal shift assay STD-NMR boron phthalimide benzamide glycosidase cancer boron neutron capture therapy n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering Issues relating to the gender schism and its effect on the career advancement of women in the Academy, especially in the field of STEM disciplines, deserve our attention and the efforts of all the scientific community to mitigate the gender gap. In order to embrace gender equality, recognize the career progression of women, and to celebrate the achievements of women in the field of bioorganic chemistry, we present contributions both from highly renowned female scientists and young female researchers who are in the early stages of their careers. This Special Issue includes fifteen manuscripts, including eleven high-quality research articles and four comprehensive review articles in the area of bioorganic chemistry, published from mid-2020 to early 2022. The scope of this Special Issue covers a wide range of topics at the organic chemistry–biology interface, including the synthesis and derivatization of natural compounds and their analogues, and the investigation of their biological activities in the human health field (for instance as antitumorals, antioxidants and antimicrobial agents), as well as their possible application in the crop protection field as agrochemicals. An example of nanoparticle-based biomaterial is also included. The techniques employed, besides organic synthesis, are in silico studies (docking procedures and molecular modeling), FT-IR spectroscopy, laser diffraction, PET, fluorescence, STD-NMR studies, enzymatic evaluation, experiments on cell lines and in vivo studies on mice. 2022-10-25T09:03:22Z 2022-10-25T09:03:22Z 2022 book ONIX_20221025_9783036549897_90 9783036549897 9783036549903 https://directory.doabooks.org/handle/20.500.12854/93236 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6135 https://mdpi.com/books/pdfview/book/6135 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4990-3 10.3390/books978-3-0365-4990-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036549897 9783036549903 288 open access |
| spellingShingle | antibiotics biochemical studies iminosugars inhibitors insect trehalase trehalose in vivo studies mammalian trehalase natural compounds selectivity interrupted Nazarov cyclization pentacyclic steroids antiproliferative activity d-annulated steroids Lewis acid dental caries enamel remineralisation hydroxyapatite amelogenin amelogenin-derived peptides leucine-rich amelogenin peptides tyrosine-rich amelogenin peptides cannabidiol molecular mechanisms neurological diseases neuroprotective effects strigolactones Strigol anti-cancer antimicrobials sustainable agriculture α,α-difluorophosphonate deoxyxylulose phosphate reductoisomerase 1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR) antimicrobial fosmidomycin isoprenoid biosynthesis 2-C-methyl-derythritol 4-phosphate (MEP) pathway multivalency gold nanoparticles enzyme inhibition Jack bean α-mannosidase aminoproline scaffold integrin targeting ligand design peptidomimetic synthesis leukocyte integrins BODIPY β-galactosidase activity PET fluorescent dispirooxindoles anticancer activity cytotoxicity 3D molecular docking p53/MDM2 interaction terpenes hydrazones penetration enhancers liposomes lipids stratum corneum laser diffraction fluorescence probe pyrene FT-IR spectroscopy heterohelicene chirality resolution enantiomers chiroptical screw-shaped compounds betulinic acid α-glucosidase inhibition mechanism postprandial hyperglycemia synergistic effect AMR persisters (p)ppGpp fragment screening thermal shift assay STD-NMR boron phthalimide benzamide glycosidase cancer boron neutron capture therapy n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering Women in Bioorganic Chemistry |
| title | Women in Bioorganic Chemistry |
| title_full | Women in Bioorganic Chemistry |
| title_fullStr | Women in Bioorganic Chemistry |
| title_full_unstemmed | Women in Bioorganic Chemistry |
| title_short | Women in Bioorganic Chemistry |
| title_sort | women in bioorganic chemistry |
| topic | antibiotics biochemical studies iminosugars inhibitors insect trehalase trehalose in vivo studies mammalian trehalase natural compounds selectivity interrupted Nazarov cyclization pentacyclic steroids antiproliferative activity d-annulated steroids Lewis acid dental caries enamel remineralisation hydroxyapatite amelogenin amelogenin-derived peptides leucine-rich amelogenin peptides tyrosine-rich amelogenin peptides cannabidiol molecular mechanisms neurological diseases neuroprotective effects strigolactones Strigol anti-cancer antimicrobials sustainable agriculture α,α-difluorophosphonate deoxyxylulose phosphate reductoisomerase 1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR) antimicrobial fosmidomycin isoprenoid biosynthesis 2-C-methyl-derythritol 4-phosphate (MEP) pathway multivalency gold nanoparticles enzyme inhibition Jack bean α-mannosidase aminoproline scaffold integrin targeting ligand design peptidomimetic synthesis leukocyte integrins BODIPY β-galactosidase activity PET fluorescent dispirooxindoles anticancer activity cytotoxicity 3D molecular docking p53/MDM2 interaction terpenes hydrazones penetration enhancers liposomes lipids stratum corneum laser diffraction fluorescence probe pyrene FT-IR spectroscopy heterohelicene chirality resolution enantiomers chiroptical screw-shaped compounds betulinic acid α-glucosidase inhibition mechanism postprandial hyperglycemia synergistic effect AMR persisters (p)ppGpp fragment screening thermal shift assay STD-NMR boron phthalimide benzamide glycosidase cancer boron neutron capture therapy n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering |
| topic_facet | antibiotics biochemical studies iminosugars inhibitors insect trehalase trehalose in vivo studies mammalian trehalase natural compounds selectivity interrupted Nazarov cyclization pentacyclic steroids antiproliferative activity d-annulated steroids Lewis acid dental caries enamel remineralisation hydroxyapatite amelogenin amelogenin-derived peptides leucine-rich amelogenin peptides tyrosine-rich amelogenin peptides cannabidiol molecular mechanisms neurological diseases neuroprotective effects strigolactones Strigol anti-cancer antimicrobials sustainable agriculture α,α-difluorophosphonate deoxyxylulose phosphate reductoisomerase 1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR) antimicrobial fosmidomycin isoprenoid biosynthesis 2-C-methyl-derythritol 4-phosphate (MEP) pathway multivalency gold nanoparticles enzyme inhibition Jack bean α-mannosidase aminoproline scaffold integrin targeting ligand design peptidomimetic synthesis leukocyte integrins BODIPY β-galactosidase activity PET fluorescent dispirooxindoles anticancer activity cytotoxicity 3D molecular docking p53/MDM2 interaction terpenes hydrazones penetration enhancers liposomes lipids stratum corneum laser diffraction fluorescence probe pyrene FT-IR spectroscopy heterohelicene chirality resolution enantiomers chiroptical screw-shaped compounds betulinic acid α-glucosidase inhibition mechanism postprandial hyperglycemia synergistic effect AMR persisters (p)ppGpp fragment screening thermal shift assay STD-NMR boron phthalimide benzamide glycosidase cancer boron neutron capture therapy n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering |
| url | ONIX_20221025_9783036549897_90 |