Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers
Volatile organic compounds (VOCs) are a diverse group of carbon-based molecules that are volatile at ambient temperatures and are emitted by an organism as a result of metabolic processes of cells and associated microbiome. The qualitative and quantitative profile of VOCs in biological fluids can va...
I tiakina i:
| Hōputu: | Online |
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| Reo: | Ingarihi |
| I whakaputaina: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Ngā marau: | |
| Urunga tuihono: | ONIX_20221025_9783036553504_110 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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| _version_ | 1869524053121826816 |
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| collection | Directory of Open Access Books |
| description | Volatile organic compounds (VOCs) are a diverse group of carbon-based molecules that are volatile at ambient temperatures and are emitted by an organism as a result of metabolic processes of cells and associated microbiome. The qualitative and quantitative profile of VOCs in biological fluids can vary depending on the physiological changes. Therefore, the pattern of volatile metabolites may reflect the presence of several diseases. This has been intensively investigated in the last few decades, resulting in an increasing number of studies focused on new volatile biomarker discovery.This reprint aimed to summarize the recent findings related to VOCs detected in various biological fluids such as breath, urine and feces for biomedical applications. The content covers various topics, including but not limited to biomedical/medical application of VOC analysis, biomarker discovery, and novel approaches for sampling and analyzing VOCs. |
| format | Online |
| id | doab-20.500.12854ir-93257 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-932572024-03-28T03:32:54Z Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers Drabińska, Natalia Lacy Costello, Ben de liquid–liquid extraction volatile compounds urine method optimization GC-MS 1H-NMR iron deficiency anaemia iron supplementation volatile organic compounds (VOCs) intestinal metabolome gut microbiome CDH microbiome VOCs spiroergometry outcome exhaled breath eNose smoking asthma COPD NTD-GC-MS breath lung cancer biomarkers volatile organic compounds urine analysis comprehensive two-dimensional gas chromatography kidney diseases urinary biomarkers hepatocellular carcinoma diagnosis headspace analysis untargeted analysis breath analysis cancer biomarkers volatolomics whole grain rye comprehensive two-dimensional gas chromatography–mass spectrometry dietary fiber e-nose electronic nose breathing rhythm mechanical ventilation anesthesia supplemental oxygen oxygen toxicity lipid peroxidation volatile aldehydes pentanal hexanal classification models dairy cows fecal headspace Mycobacterium avium ssp. paratuberculosis (MAP) paratuberculosis random forest stable air volatile organic compound (VOC) biomarker MCC–IMS ventilator-induced lung injury metabolome feces neonates fermentation protein carbohydrate short chain fatty acid metabolites volatile organic compound acute gastritis antibiotic treatment treatment dynamics: microbiota mid-infrared spectroscopy short-chain fatty acid alpha-keto acid Helicobacter pylori MOX sensors low sensing chamber volume calibration transfer standard samples piecewise direct standardization correlation alignment breath sampling pattern recognition thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry Volatile organic compounds (VOCs) are a diverse group of carbon-based molecules that are volatile at ambient temperatures and are emitted by an organism as a result of metabolic processes of cells and associated microbiome. The qualitative and quantitative profile of VOCs in biological fluids can vary depending on the physiological changes. Therefore, the pattern of volatile metabolites may reflect the presence of several diseases. This has been intensively investigated in the last few decades, resulting in an increasing number of studies focused on new volatile biomarker discovery.This reprint aimed to summarize the recent findings related to VOCs detected in various biological fluids such as breath, urine and feces for biomedical applications. The content covers various topics, including but not limited to biomedical/medical application of VOC analysis, biomarker discovery, and novel approaches for sampling and analyzing VOCs. 2022-10-25T09:04:16Z 2022-10-25T09:04:16Z 2022 book ONIX_20221025_9783036553504_110 9783036553504 9783036553498 https://directory.doabooks.org/handle/20.500.12854/93257 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6155 https://mdpi.com/books/pdfview/book/6155 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5349-8 10.3390/books978-3-0365-5349-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036553504 9783036553498 224 open access |
| spellingShingle | liquid–liquid extraction volatile compounds urine method optimization GC-MS 1H-NMR iron deficiency anaemia iron supplementation volatile organic compounds (VOCs) intestinal metabolome gut microbiome CDH microbiome VOCs spiroergometry outcome exhaled breath eNose smoking asthma COPD NTD-GC-MS breath lung cancer biomarkers volatile organic compounds urine analysis comprehensive two-dimensional gas chromatography kidney diseases urinary biomarkers hepatocellular carcinoma diagnosis headspace analysis untargeted analysis breath analysis cancer biomarkers volatolomics whole grain rye comprehensive two-dimensional gas chromatography–mass spectrometry dietary fiber e-nose electronic nose breathing rhythm mechanical ventilation anesthesia supplemental oxygen oxygen toxicity lipid peroxidation volatile aldehydes pentanal hexanal classification models dairy cows fecal headspace Mycobacterium avium ssp. paratuberculosis (MAP) paratuberculosis random forest stable air volatile organic compound (VOC) biomarker MCC–IMS ventilator-induced lung injury metabolome feces neonates fermentation protein carbohydrate short chain fatty acid metabolites volatile organic compound acute gastritis antibiotic treatment treatment dynamics: microbiota mid-infrared spectroscopy short-chain fatty acid alpha-keto acid Helicobacter pylori MOX sensors low sensing chamber volume calibration transfer standard samples piecewise direct standardization correlation alignment breath sampling pattern recognition thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers |
| title | Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers |
| title_full | Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers |
| title_fullStr | Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers |
| title_full_unstemmed | Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers |
| title_short | Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers |
| title_sort | recent advances in volatile organic compound analysis as diagnostic biomarkers |
| topic | liquid–liquid extraction volatile compounds urine method optimization GC-MS 1H-NMR iron deficiency anaemia iron supplementation volatile organic compounds (VOCs) intestinal metabolome gut microbiome CDH microbiome VOCs spiroergometry outcome exhaled breath eNose smoking asthma COPD NTD-GC-MS breath lung cancer biomarkers volatile organic compounds urine analysis comprehensive two-dimensional gas chromatography kidney diseases urinary biomarkers hepatocellular carcinoma diagnosis headspace analysis untargeted analysis breath analysis cancer biomarkers volatolomics whole grain rye comprehensive two-dimensional gas chromatography–mass spectrometry dietary fiber e-nose electronic nose breathing rhythm mechanical ventilation anesthesia supplemental oxygen oxygen toxicity lipid peroxidation volatile aldehydes pentanal hexanal classification models dairy cows fecal headspace Mycobacterium avium ssp. paratuberculosis (MAP) paratuberculosis random forest stable air volatile organic compound (VOC) biomarker MCC–IMS ventilator-induced lung injury metabolome feces neonates fermentation protein carbohydrate short chain fatty acid metabolites volatile organic compound acute gastritis antibiotic treatment treatment dynamics: microbiota mid-infrared spectroscopy short-chain fatty acid alpha-keto acid Helicobacter pylori MOX sensors low sensing chamber volume calibration transfer standard samples piecewise direct standardization correlation alignment breath sampling pattern recognition thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | liquid–liquid extraction volatile compounds urine method optimization GC-MS 1H-NMR iron deficiency anaemia iron supplementation volatile organic compounds (VOCs) intestinal metabolome gut microbiome CDH microbiome VOCs spiroergometry outcome exhaled breath eNose smoking asthma COPD NTD-GC-MS breath lung cancer biomarkers volatile organic compounds urine analysis comprehensive two-dimensional gas chromatography kidney diseases urinary biomarkers hepatocellular carcinoma diagnosis headspace analysis untargeted analysis breath analysis cancer biomarkers volatolomics whole grain rye comprehensive two-dimensional gas chromatography–mass spectrometry dietary fiber e-nose electronic nose breathing rhythm mechanical ventilation anesthesia supplemental oxygen oxygen toxicity lipid peroxidation volatile aldehydes pentanal hexanal classification models dairy cows fecal headspace Mycobacterium avium ssp. paratuberculosis (MAP) paratuberculosis random forest stable air volatile organic compound (VOC) biomarker MCC–IMS ventilator-induced lung injury metabolome feces neonates fermentation protein carbohydrate short chain fatty acid metabolites volatile organic compound acute gastritis antibiotic treatment treatment dynamics: microbiota mid-infrared spectroscopy short-chain fatty acid alpha-keto acid Helicobacter pylori MOX sensors low sensing chamber volume calibration transfer standard samples piecewise direct standardization correlation alignment breath sampling pattern recognition thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | ONIX_20221025_9783036553504_110 |