Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa
This Special Issue focuses on the effects of hydrostatic pressure on biological systems and the use of these effects for exploring the structure, function, and molecular dynamics of biological macromolecules and their ensembles. Here, we present a selection of papers highlighting new experimental fi...
Збережено в:
| Формат: | Online |
|---|---|
| Мова: | Англійська |
| Опубліковано: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
|
| Предмети: | |
| Онлайн доступ: | ONIX_20221117_9783036546728_90 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
| _version_ | 1869514909427957760 |
|---|---|
| collection | Directory of Open Access Books |
| description | This Special Issue focuses on the effects of hydrostatic pressure on biological systems and the use of these effects for exploring the structure, function, and molecular dynamics of biological macromolecules and their ensembles. Here, we present a selection of papers highlighting new experimental findings and new theoretical concepts in high-pressure biosciences. In these studies, the authors combine pressure perturbation approaches with NMR and optical spectroscopy, kinetic and thermodynamic techniques, functional genomics and transcriptomics, and molecular dynamics simulations to gain new insights into the conformational dynamics of proteins and nucleic acids and to better understand the mechanisms of high-pressure adaptation in piezophiles. The articles collected in this issue demonstrate the unique exploratory potential of the pressure perturbation approach for biochemistry, biophysics, mechanistic enzymology, and evolutionary biology. |
| format | Online |
| id | doab-20.500.12854ir-93833 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-938332024-03-28T03:31:10Z Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa Davydov, Dmitri Jung, Christiane protein folding NMR high hydrostatic pressure thermodynamic stability protein–ligand binding high pressure Martian salts perchlorate BSA ANS viroid hydrostatic pressure temperature structure–activity relationship RNA World n/a G-quadruplex i-motif volumetric properties pressure-temperature phase diagram thermodynamics hepatitis B DNA oligo FRET FTIR spectroscopy pressure volume change TMPyP4 deep-sea adaptations compressibility cavities potential energy landscape yeast Saccharomyces cerevisiae high-pressure response genetic manipulation transcriptomics piezophysiology Anfinsen’s dogma native state N unfolded state U fibril state F protofibrils hen lysozyme circular dichroism 1H NMR spectroscopy atomic force microscopy cytochrome P450 reductase conformational change pressure-perturbation spectroscopy protein hydration reduction kinetics stop-flow spectroscopy Sorghum bicolor thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry This Special Issue focuses on the effects of hydrostatic pressure on biological systems and the use of these effects for exploring the structure, function, and molecular dynamics of biological macromolecules and their ensembles. Here, we present a selection of papers highlighting new experimental findings and new theoretical concepts in high-pressure biosciences. In these studies, the authors combine pressure perturbation approaches with NMR and optical spectroscopy, kinetic and thermodynamic techniques, functional genomics and transcriptomics, and molecular dynamics simulations to gain new insights into the conformational dynamics of proteins and nucleic acids and to better understand the mechanisms of high-pressure adaptation in piezophiles. The articles collected in this issue demonstrate the unique exploratory potential of the pressure perturbation approach for biochemistry, biophysics, mechanistic enzymology, and evolutionary biology. 2022-11-17T16:27:00Z 2022-11-17T16:27:00Z 2022 book ONIX_20221117_9783036546728_90 9783036546728 9783036546711 https://directory.doabooks.org/handle/20.500.12854/93833 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6262 https://mdpi.com/books/pdfview/book/6262 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4672-8 10.3390/books978-3-0365-4672-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036546728 9783036546711 160 Basel open access |
| spellingShingle | protein folding NMR high hydrostatic pressure thermodynamic stability protein–ligand binding high pressure Martian salts perchlorate BSA ANS viroid hydrostatic pressure temperature structure–activity relationship RNA World n/a G-quadruplex i-motif volumetric properties pressure-temperature phase diagram thermodynamics hepatitis B DNA oligo FRET FTIR spectroscopy pressure volume change TMPyP4 deep-sea adaptations compressibility cavities potential energy landscape yeast Saccharomyces cerevisiae high-pressure response genetic manipulation transcriptomics piezophysiology Anfinsen’s dogma native state N unfolded state U fibril state F protofibrils hen lysozyme circular dichroism 1H NMR spectroscopy atomic force microscopy cytochrome P450 reductase conformational change pressure-perturbation spectroscopy protein hydration reduction kinetics stop-flow spectroscopy Sorghum bicolor thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa |
| title | Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa |
| title_full | Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa |
| title_fullStr | Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa |
| title_full_unstemmed | Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa |
| title_short | Pressure Perturbation Approach in Biochemistry and Structural Biology. In memoriam of Dr. Gaston Hui Bon Hoa |
| title_sort | pressure perturbation approach in biochemistry and structural biology in memoriam of dr gaston hui bon hoa |
| topic | protein folding NMR high hydrostatic pressure thermodynamic stability protein–ligand binding high pressure Martian salts perchlorate BSA ANS viroid hydrostatic pressure temperature structure–activity relationship RNA World n/a G-quadruplex i-motif volumetric properties pressure-temperature phase diagram thermodynamics hepatitis B DNA oligo FRET FTIR spectroscopy pressure volume change TMPyP4 deep-sea adaptations compressibility cavities potential energy landscape yeast Saccharomyces cerevisiae high-pressure response genetic manipulation transcriptomics piezophysiology Anfinsen’s dogma native state N unfolded state U fibril state F protofibrils hen lysozyme circular dichroism 1H NMR spectroscopy atomic force microscopy cytochrome P450 reductase conformational change pressure-perturbation spectroscopy protein hydration reduction kinetics stop-flow spectroscopy Sorghum bicolor thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | protein folding NMR high hydrostatic pressure thermodynamic stability protein–ligand binding high pressure Martian salts perchlorate BSA ANS viroid hydrostatic pressure temperature structure–activity relationship RNA World n/a G-quadruplex i-motif volumetric properties pressure-temperature phase diagram thermodynamics hepatitis B DNA oligo FRET FTIR spectroscopy pressure volume change TMPyP4 deep-sea adaptations compressibility cavities potential energy landscape yeast Saccharomyces cerevisiae high-pressure response genetic manipulation transcriptomics piezophysiology Anfinsen’s dogma native state N unfolded state U fibril state F protofibrils hen lysozyme circular dichroism 1H NMR spectroscopy atomic force microscopy cytochrome P450 reductase conformational change pressure-perturbation spectroscopy protein hydration reduction kinetics stop-flow spectroscopy Sorghum bicolor thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20221117_9783036546728_90 |