The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis

How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue en...

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Jezik:engleski
Izdano: Taylor & Francis 2022
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collection Directory of Open Access Books
description How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for governing stem cell fate. In addition, increasing evidence suggests that abnormal interaction of stem cells with their niche is responsible for altered cell function leading to malignant transformation. This book discusses some of the recent advances in stem cell research that may help understanding the properties of the niche that govern stem cell fate. Technical topics discussed include:Stem cell biologyCancer stem cellsStem cell interactions with biomaterialsEngineering the stem cell microenvironmentStem cells in tissue regeneration and repairThe Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book emerges as a result of the scientific contributions presented and discussed during the fifth Disputationes Workshop held in Aalborg (Denmark) in April 2014. The stem cell microenvironment and its role in regenerative medicine and cancer pathogenesis is ideal for academic staff and master/research students in biomedical and health sciences
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publishDate 2022
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spelling doab-20.500.12854ir-943122025-08-13T13:41:50Z The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis Pennisi, Cristian Pablo Prasad, Mayuri Sinha Rameshwar, Pranela Cellular biology (cytology) Pre-clinical medicine: basic sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for governing stem cell fate. In addition, increasing evidence suggests that abnormal interaction of stem cells with their niche is responsible for altered cell function leading to malignant transformation. This book discusses some of the recent advances in stem cell research that may help understanding the properties of the niche that govern stem cell fate. Technical topics discussed include:Stem cell biologyCancer stem cellsStem cell interactions with biomaterialsEngineering the stem cell microenvironmentStem cells in tissue regeneration and repairThe Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book emerges as a result of the scientific contributions presented and discussed during the fifth Disputationes Workshop held in Aalborg (Denmark) in April 2014. The stem cell microenvironment and its role in regenerative medicine and cancer pathogenesis is ideal for academic staff and master/research students in biomedical and health sciences 2022-11-29T04:03:30Z 2022-11-29T04:03:30Z 2022-11-28T16:03:56Z 2017 book ONIX_20221128_9781000794113_26 https://library.oapen.org/handle/20.500.12657/59742 9781000794113 9788793379930 9781003339779 https://directory.doabooks.org/handle/20.500.12854/94312 eng open access image/jpeg image/jpeg n/a n/a https://library.oapen.org/bitstream/20.500.12657/59742/1/9781000794113.pdf https://library.oapen.org/bitstream/20.500.12657/59742/1/9781000794113.pdf Taylor & Francis River Publishers 10.1201/9781003339779 10.1201/9781003339779 fa69b019-f4ee-4979-8d42-c6b6c476b5f0 9781000794113 9788793379930 9781003339779 River Publishers 142 open access
spellingShingle Cellular biology (cytology)
Pre-clinical medicine: basic sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences
The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
title The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
title_full The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
title_fullStr The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
title_full_unstemmed The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
title_short The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
title_sort stem cell microenvironment and its role in regenerative medicine and cancer pathogenesis
topic Cellular biology (cytology)
Pre-clinical medicine: basic sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences
topic_facet Cellular biology (cytology)
Pre-clinical medicine: basic sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences
url ONIX_20221128_9781000794113_26