Targeting the Microbiome for Disease Diagnosis and Therapy
Background: The gut microbiota is emerging as a pivotal player in the pathogenesis of many non-communicable diseases. Thus, it has been proposed as a new diagnostic and therapeutic target.Aim and scope: This Special Issue will focus on the microbiome as a potential target of new personalized therapi...
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| Médium: | Online |
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| Jazyk: | angličtina |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| On-line přístup: | ONIX_20221206_9783036556123_13 |
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| collection | Directory of Open Access Books |
| description | Background: The gut microbiota is emerging as a pivotal player in the pathogenesis of many non-communicable diseases. Thus, it has been proposed as a new diagnostic and therapeutic target.Aim and scope: This Special Issue will focus on the microbiome as a potential target of new personalized therapies or diagnostic tools.History: In recent decades, the gut microbiome has been deeply investigated, and many studies have provided new information on the role of dysbiosis in many gastrointestinal and extra-gastrointestinal diseases. Recently, in addition to its phylogenetic characterization, new information has become available regarding the function of the gut microbiota, thanks to proteomic and metabolomic analyses.Cutting-edge research: The therapeutic modulation of the gut microbiota based on different strategies, including diet modification, antibiotics, prebiotics, probiotics, and, last but not least, fecal microbiota transplantation, has been tested for the treatment of various diseases. Recently, the possible applications and modalities of gut microbiota modulation have been increasingly expanding.We have collected original clinical or pre-clinical research papers and reviews focusing on the use of the microbiome for disease diagnosis, monitoring, or therapy and suggesting new possible gut microbiota-based approaches for personalized care. |
| format | Online |
| id | doab-20.500.12854ir-94490 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-944902024-03-31T13:09:47Z Targeting the Microbiome for Disease Diagnosis and Therapy Laterza, Lucrezia Graves–Basedow’s diseases Hashimoto’s thyroiditis autoimmunity gut microbiota irritable bowel syndrome microbiota microbiome food components nutrients hematopoietic stem cell transplantation fecal microbiota transplantation aGvHD antibiotic-resistant bacteria cystic fibrosis rabbits intestinal dysbiosis feces microbiome beta-blocker hemodialysis next-generation sequencing propensity score matching methods violin plots random sampling analytical reproducibility fecal matter transplantation data disease subtypes personalized medicine maltodextrin dip test gallstone disease 16S rDNA gene diversity blood biochemical characteristics mesothelioma 16S RNA sequencing species probiotics and gut disease probiotics and acute diverticulitis probiotics and diverticular disease probiotics mechanism of action IgA Nephropathy rifaximin α1KI-CD89Tg mice children intermittent hypoxemia obstructive sleep apnea tonsil weight status oral microbiota rheumatology diseases biomarkers artificial intelligence machine learning rheumatoid arthritis Sjogren’s syndrome systemic lupus erythematosus endometrial cancer endometrial microbiome gut microbiome dysbiosis estrogen metabolism estrobolome inflammation antitumour treatment prebiotics probiotics schizophrenia depression anxiety functional genes thymoma genera driver mutation cardiovascular diseases critically ill intestinal permeability recurrent cystitis n/a thema EDItEUR::M Medicine and Nursing Background: The gut microbiota is emerging as a pivotal player in the pathogenesis of many non-communicable diseases. Thus, it has been proposed as a new diagnostic and therapeutic target.Aim and scope: This Special Issue will focus on the microbiome as a potential target of new personalized therapies or diagnostic tools.History: In recent decades, the gut microbiome has been deeply investigated, and many studies have provided new information on the role of dysbiosis in many gastrointestinal and extra-gastrointestinal diseases. Recently, in addition to its phylogenetic characterization, new information has become available regarding the function of the gut microbiota, thanks to proteomic and metabolomic analyses.Cutting-edge research: The therapeutic modulation of the gut microbiota based on different strategies, including diet modification, antibiotics, prebiotics, probiotics, and, last but not least, fecal microbiota transplantation, has been tested for the treatment of various diseases. Recently, the possible applications and modalities of gut microbiota modulation have been increasingly expanding.We have collected original clinical or pre-clinical research papers and reviews focusing on the use of the microbiome for disease diagnosis, monitoring, or therapy and suggesting new possible gut microbiota-based approaches for personalized care. 2022-12-06T16:07:57Z 2022-12-06T16:07:57Z 2022 book ONIX_20221206_9783036556123_13 9783036556123 9783036556116 https://directory.doabooks.org/handle/20.500.12854/94490 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6314 https://mdpi.com/books/pdfview/book/6314 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5611-6 10.3390/books978-3-0365-5611-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036556123 9783036556116 280 Basel open access |
| spellingShingle | Graves–Basedow’s diseases Hashimoto’s thyroiditis autoimmunity gut microbiota irritable bowel syndrome microbiota microbiome food components nutrients hematopoietic stem cell transplantation fecal microbiota transplantation aGvHD antibiotic-resistant bacteria cystic fibrosis rabbits intestinal dysbiosis feces microbiome beta-blocker hemodialysis next-generation sequencing propensity score matching methods violin plots random sampling analytical reproducibility fecal matter transplantation data disease subtypes personalized medicine maltodextrin dip test gallstone disease 16S rDNA gene diversity blood biochemical characteristics mesothelioma 16S RNA sequencing species probiotics and gut disease probiotics and acute diverticulitis probiotics and diverticular disease probiotics mechanism of action IgA Nephropathy rifaximin α1KI-CD89Tg mice children intermittent hypoxemia obstructive sleep apnea tonsil weight status oral microbiota rheumatology diseases biomarkers artificial intelligence machine learning rheumatoid arthritis Sjogren’s syndrome systemic lupus erythematosus endometrial cancer endometrial microbiome gut microbiome dysbiosis estrogen metabolism estrobolome inflammation antitumour treatment prebiotics probiotics schizophrenia depression anxiety functional genes thymoma genera driver mutation cardiovascular diseases critically ill intestinal permeability recurrent cystitis n/a thema EDItEUR::M Medicine and Nursing Targeting the Microbiome for Disease Diagnosis and Therapy |
| title | Targeting the Microbiome for Disease Diagnosis and Therapy |
| title_full | Targeting the Microbiome for Disease Diagnosis and Therapy |
| title_fullStr | Targeting the Microbiome for Disease Diagnosis and Therapy |
| title_full_unstemmed | Targeting the Microbiome for Disease Diagnosis and Therapy |
| title_short | Targeting the Microbiome for Disease Diagnosis and Therapy |
| title_sort | targeting the microbiome for disease diagnosis and therapy |
| topic | Graves–Basedow’s diseases Hashimoto’s thyroiditis autoimmunity gut microbiota irritable bowel syndrome microbiota microbiome food components nutrients hematopoietic stem cell transplantation fecal microbiota transplantation aGvHD antibiotic-resistant bacteria cystic fibrosis rabbits intestinal dysbiosis feces microbiome beta-blocker hemodialysis next-generation sequencing propensity score matching methods violin plots random sampling analytical reproducibility fecal matter transplantation data disease subtypes personalized medicine maltodextrin dip test gallstone disease 16S rDNA gene diversity blood biochemical characteristics mesothelioma 16S RNA sequencing species probiotics and gut disease probiotics and acute diverticulitis probiotics and diverticular disease probiotics mechanism of action IgA Nephropathy rifaximin α1KI-CD89Tg mice children intermittent hypoxemia obstructive sleep apnea tonsil weight status oral microbiota rheumatology diseases biomarkers artificial intelligence machine learning rheumatoid arthritis Sjogren’s syndrome systemic lupus erythematosus endometrial cancer endometrial microbiome gut microbiome dysbiosis estrogen metabolism estrobolome inflammation antitumour treatment prebiotics probiotics schizophrenia depression anxiety functional genes thymoma genera driver mutation cardiovascular diseases critically ill intestinal permeability recurrent cystitis n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | Graves–Basedow’s diseases Hashimoto’s thyroiditis autoimmunity gut microbiota irritable bowel syndrome microbiota microbiome food components nutrients hematopoietic stem cell transplantation fecal microbiota transplantation aGvHD antibiotic-resistant bacteria cystic fibrosis rabbits intestinal dysbiosis feces microbiome beta-blocker hemodialysis next-generation sequencing propensity score matching methods violin plots random sampling analytical reproducibility fecal matter transplantation data disease subtypes personalized medicine maltodextrin dip test gallstone disease 16S rDNA gene diversity blood biochemical characteristics mesothelioma 16S RNA sequencing species probiotics and gut disease probiotics and acute diverticulitis probiotics and diverticular disease probiotics mechanism of action IgA Nephropathy rifaximin α1KI-CD89Tg mice children intermittent hypoxemia obstructive sleep apnea tonsil weight status oral microbiota rheumatology diseases biomarkers artificial intelligence machine learning rheumatoid arthritis Sjogren’s syndrome systemic lupus erythematosus endometrial cancer endometrial microbiome gut microbiome dysbiosis estrogen metabolism estrobolome inflammation antitumour treatment prebiotics probiotics schizophrenia depression anxiety functional genes thymoma genera driver mutation cardiovascular diseases critically ill intestinal permeability recurrent cystitis n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20221206_9783036556123_13 |