Quantitative PET and SPECT
Since the introduction of personalized medicine, the primary focus of imaging has moved from detection and diagnosis to tissue characterization, the determination of prognosis, prediction of treatment efficacy, and measurement of treatment response. Precision (personalized) imaging heavily relies on...
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| Format: | Online |
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| Langue: | anglais |
| Publié: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Sujets: | |
| Accès en ligne: | ONIX_20221206_9783036556154_68 |
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| _version_ | 1869523784966340608 |
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| collection | Directory of Open Access Books |
| description | Since the introduction of personalized medicine, the primary focus of imaging has moved from detection and diagnosis to tissue characterization, the determination of prognosis, prediction of treatment efficacy, and measurement of treatment response. Precision (personalized) imaging heavily relies on the use of hybrid technologies and quantitative imaging biomarkers. The growing number of promising theragnostics require accurate quantification for pre- and post-treatment dosimetry. Furthermore, quantification is required in the pharmacokinetic analysis of new tracers and drugs and in the assessment of drug resistance. Positron Emission Tomography (PET) is, by nature, a quantitative imaging tool, relating the time–activity concentration in tissues and the basic functional parameters governing the biological processes being studied. Recent innovations in single photon emission computed tomography (SPECT) reconstruction techniques have allowed for SPECT to move from relative/semi-quantitative measures to absolute quantification. The strength of PET and SPECT is that they permit whole-body molecular imaging in a noninvasive way, evaluating multiple disease sites. Furthermore, serial scanning can be performed, allowing for the measurement of functional changes over time during therapeutic interventions. This Special Issue highlights the hot topics on quantitative PET and SPECT. |
| format | Online |
| id | doab-20.500.12854ir-94545 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-945452024-03-31T13:10:35Z Quantitative PET and SPECT de Geus-Oei, Lioe-Fee van Velden, Floris H. P. PET SPECT PET/CT SPECT/CT Absolute quantification Quantitative accuracy Dynamic PET Phantoms Repeatability Tumor delineation Prognosis Dosimetry Radiomics Artificial intelligence Deep learning Imaging biomarkers Tumor segmentation Harmonization thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine Since the introduction of personalized medicine, the primary focus of imaging has moved from detection and diagnosis to tissue characterization, the determination of prognosis, prediction of treatment efficacy, and measurement of treatment response. Precision (personalized) imaging heavily relies on the use of hybrid technologies and quantitative imaging biomarkers. The growing number of promising theragnostics require accurate quantification for pre- and post-treatment dosimetry. Furthermore, quantification is required in the pharmacokinetic analysis of new tracers and drugs and in the assessment of drug resistance. Positron Emission Tomography (PET) is, by nature, a quantitative imaging tool, relating the time–activity concentration in tissues and the basic functional parameters governing the biological processes being studied. Recent innovations in single photon emission computed tomography (SPECT) reconstruction techniques have allowed for SPECT to move from relative/semi-quantitative measures to absolute quantification. The strength of PET and SPECT is that they permit whole-body molecular imaging in a noninvasive way, evaluating multiple disease sites. Furthermore, serial scanning can be performed, allowing for the measurement of functional changes over time during therapeutic interventions. This Special Issue highlights the hot topics on quantitative PET and SPECT. 2022-12-06T16:11:03Z 2022-12-06T16:11:03Z 2022 book ONIX_20221206_9783036556154_68 9783036556154 9783036556161 https://directory.doabooks.org/handle/20.500.12854/94545 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6380 https://mdpi.com/books/pdfview/book/6380 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5616-1 10.3390/books978-3-0365-5616-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036556154 9783036556161 212 Basel open access |
| spellingShingle | PET SPECT PET/CT SPECT/CT Absolute quantification Quantitative accuracy Dynamic PET Phantoms Repeatability Tumor delineation Prognosis Dosimetry Radiomics Artificial intelligence Deep learning Imaging biomarkers Tumor segmentation Harmonization thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine Quantitative PET and SPECT |
| title | Quantitative PET and SPECT |
| title_full | Quantitative PET and SPECT |
| title_fullStr | Quantitative PET and SPECT |
| title_full_unstemmed | Quantitative PET and SPECT |
| title_short | Quantitative PET and SPECT |
| title_sort | quantitative pet and spect |
| topic | PET SPECT PET/CT SPECT/CT Absolute quantification Quantitative accuracy Dynamic PET Phantoms Repeatability Tumor delineation Prognosis Dosimetry Radiomics Artificial intelligence Deep learning Imaging biomarkers Tumor segmentation Harmonization thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine |
| topic_facet | PET SPECT PET/CT SPECT/CT Absolute quantification Quantitative accuracy Dynamic PET Phantoms Repeatability Tumor delineation Prognosis Dosimetry Radiomics Artificial intelligence Deep learning Imaging biomarkers Tumor segmentation Harmonization thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine |
| url | ONIX_20221206_9783036556154_68 |