Developmental Exposure to Environmental Contaminants

Development provides an especially sensitive window whereby environmental contaminants can have significant and lasting effects on the morphology and function of many organs and systems. The importance of understanding developmental effects of environmental contaminants extends not only to developme...

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collection Directory of Open Access Books
description Development provides an especially sensitive window whereby environmental contaminants can have significant and lasting effects on the morphology and function of many organs and systems. The importance of understanding developmental effects of environmental contaminants extends not only to developmental stages, but also to encompass the hypotheses of the developmental or fetal origins of adult disease. Such effects of environmental contaminants during development extend to health outcomes that can persist in adulthood, first become apparent in adulthood, or manifest in adulthood but only after a second hit/stressor. The diverse nature of possible environmental contaminants, ranging from persistent organic pollutants to emerging contaminants of concern, along with the diverse range of health implications, including autism, diabetes, cancer, infertility, and lower urinary tract function, make understanding developmental effects of environmental contaminants an ever growing and important field of study.This Special Issue aims to explore a variety of topics in line with the aims and scope of Toxics. Specifically, topics related to the developmental effects of environmental contaminants and/or their metabolites on the molecular, cellular, tissue, organ, organ system or organism, including mechanisms of toxicity, metabolism, risk assessment and management, as well as multiple stressor impacts in the context of aging or disease progression following developmental exposures.
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language eng
publishDate 2023
publishDateRange 2023
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-958362024-03-31T13:08:15Z Developmental Exposure to Environmental Contaminants Stietz, Kimberly Keil Baker, Tracie Plavicki, Jessica arsenic synaptic transmission long-term potentiation hippocampus development lower urinary tract bladder inflammation POPs developmental basis of adult disease multigenerational toxicants bronchopulmonary dysplasia therapeutics lung development selective serotonin reuptake inhibitor perinatal mortality neonatal morbidity fluoxetine sertraline endocrine-disrupting chemicals (EDC) Aroclor 1221 (A1221) PCBs vinclozolin social behavior sex differences transgenerational epigenetic endocrine-disrupting chemical (EDC) polychlorinated biphenyl (PCB) mating behavior paced mating ultrasonic vocalization (USV) estradiol triclosan triclocarbon detergents 4-nonylphenol Danio rerio zebrafish environmental toxicity aquatic environment ground water chemicals lower urinary tract dysfunction lower urinary tract symptoms BPH prostate axonal growth developmental neurotoxicity neuronal morphogenesis PBDE reactive oxygen species thyroid hormone pesticides prebiotic intestinal dysbiosis perigestational dysmetabolism risk factor behavior chemical screening literature comparison developmental toxicity negative control positive control rapid testing PFAS PFAS mixtures epigenetics microglia valproic acid primary motor cortex thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology Development provides an especially sensitive window whereby environmental contaminants can have significant and lasting effects on the morphology and function of many organs and systems. The importance of understanding developmental effects of environmental contaminants extends not only to developmental stages, but also to encompass the hypotheses of the developmental or fetal origins of adult disease. Such effects of environmental contaminants during development extend to health outcomes that can persist in adulthood, first become apparent in adulthood, or manifest in adulthood but only after a second hit/stressor. The diverse nature of possible environmental contaminants, ranging from persistent organic pollutants to emerging contaminants of concern, along with the diverse range of health implications, including autism, diabetes, cancer, infertility, and lower urinary tract function, make understanding developmental effects of environmental contaminants an ever growing and important field of study.This Special Issue aims to explore a variety of topics in line with the aims and scope of Toxics. Specifically, topics related to the developmental effects of environmental contaminants and/or their metabolites on the molecular, cellular, tissue, organ, organ system or organism, including mechanisms of toxicity, metabolism, risk assessment and management, as well as multiple stressor impacts in the context of aging or disease progression following developmental exposures. 2023-01-05T12:35:02Z 2023-01-05T12:35:02Z 2022 book ONIX_20230105_9783036558868_65 9783036558868 9783036558851 https://directory.doabooks.org/handle/20.500.12854/95836 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6492 https://mdpi.com/books/pdfview/book/6492 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-5885-1 10.3390/books978-3-0365-5885-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036558868 9783036558851 256 Basel open access
spellingShingle arsenic
synaptic transmission
long-term potentiation
hippocampus
development
lower urinary tract
bladder
inflammation
POPs
developmental basis of adult disease
multigenerational
toxicants
bronchopulmonary dysplasia
therapeutics
lung development
selective serotonin reuptake inhibitor
perinatal mortality
neonatal morbidity
fluoxetine
sertraline
endocrine-disrupting chemicals (EDC)
Aroclor 1221 (A1221)
PCBs
vinclozolin
social behavior
sex differences
transgenerational
epigenetic
endocrine-disrupting chemical (EDC)
polychlorinated biphenyl (PCB)
mating behavior
paced mating
ultrasonic vocalization (USV)
estradiol
triclosan
triclocarbon
detergents
4-nonylphenol
Danio rerio
zebrafish
environmental toxicity
aquatic environment
ground water chemicals
lower urinary tract dysfunction
lower urinary tract symptoms
BPH
prostate
axonal growth
developmental neurotoxicity
neuronal morphogenesis
PBDE
reactive oxygen species
thyroid hormone
pesticides
prebiotic
intestinal dysbiosis
perigestational
dysmetabolism
risk factor
behavior
chemical screening
literature comparison
developmental toxicity
negative control
positive control
rapid testing
PFAS
PFAS mixtures
epigenetics
microglia
valproic acid
primary motor cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology
Developmental Exposure to Environmental Contaminants
title Developmental Exposure to Environmental Contaminants
title_full Developmental Exposure to Environmental Contaminants
title_fullStr Developmental Exposure to Environmental Contaminants
title_full_unstemmed Developmental Exposure to Environmental Contaminants
title_short Developmental Exposure to Environmental Contaminants
title_sort developmental exposure to environmental contaminants
topic arsenic
synaptic transmission
long-term potentiation
hippocampus
development
lower urinary tract
bladder
inflammation
POPs
developmental basis of adult disease
multigenerational
toxicants
bronchopulmonary dysplasia
therapeutics
lung development
selective serotonin reuptake inhibitor
perinatal mortality
neonatal morbidity
fluoxetine
sertraline
endocrine-disrupting chemicals (EDC)
Aroclor 1221 (A1221)
PCBs
vinclozolin
social behavior
sex differences
transgenerational
epigenetic
endocrine-disrupting chemical (EDC)
polychlorinated biphenyl (PCB)
mating behavior
paced mating
ultrasonic vocalization (USV)
estradiol
triclosan
triclocarbon
detergents
4-nonylphenol
Danio rerio
zebrafish
environmental toxicity
aquatic environment
ground water chemicals
lower urinary tract dysfunction
lower urinary tract symptoms
BPH
prostate
axonal growth
developmental neurotoxicity
neuronal morphogenesis
PBDE
reactive oxygen species
thyroid hormone
pesticides
prebiotic
intestinal dysbiosis
perigestational
dysmetabolism
risk factor
behavior
chemical screening
literature comparison
developmental toxicity
negative control
positive control
rapid testing
PFAS
PFAS mixtures
epigenetics
microglia
valproic acid
primary motor cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology
topic_facet arsenic
synaptic transmission
long-term potentiation
hippocampus
development
lower urinary tract
bladder
inflammation
POPs
developmental basis of adult disease
multigenerational
toxicants
bronchopulmonary dysplasia
therapeutics
lung development
selective serotonin reuptake inhibitor
perinatal mortality
neonatal morbidity
fluoxetine
sertraline
endocrine-disrupting chemicals (EDC)
Aroclor 1221 (A1221)
PCBs
vinclozolin
social behavior
sex differences
transgenerational
epigenetic
endocrine-disrupting chemical (EDC)
polychlorinated biphenyl (PCB)
mating behavior
paced mating
ultrasonic vocalization (USV)
estradiol
triclosan
triclocarbon
detergents
4-nonylphenol
Danio rerio
zebrafish
environmental toxicity
aquatic environment
ground water chemicals
lower urinary tract dysfunction
lower urinary tract symptoms
BPH
prostate
axonal growth
developmental neurotoxicity
neuronal morphogenesis
PBDE
reactive oxygen species
thyroid hormone
pesticides
prebiotic
intestinal dysbiosis
perigestational
dysmetabolism
risk factor
behavior
chemical screening
literature comparison
developmental toxicity
negative control
positive control
rapid testing
PFAS
PFAS mixtures
epigenetics
microglia
valproic acid
primary motor cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology
url ONIX_20230105_9783036558868_65