Dietary Curcumin and Health Effects

The Special Issue provides twelve contributions, of which three original articles, seven narrative reviews, one systematic review, and one meta-analysis that, altogether, offer a multifaceted and multidisciplinary overview that allows to draw a picture as intriguing and fascinating as possible on th...

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Urunga tuihono:ONIX_20230202_9783036560878_91
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collection Directory of Open Access Books
description The Special Issue provides twelve contributions, of which three original articles, seven narrative reviews, one systematic review, and one meta-analysis that, altogether, offer a multifaceted and multidisciplinary overview that allows to draw a picture as intriguing and fascinating as possible on the benefits of curcumin and also to suggest potential fields of activities still to be explored. Among the biological activities exerted by curcumin, the anti-oxidative and anti-inflammatory properties reported in many studies make it a potential effective tool in preventing and counteracting chronic-degenerative diseases, very often associated with obesity and aging, such as cardiovascular diseases, T2D, metabolic dysfunctions, neurodegenerative diseases, and cancer, all of them characterized by the presence of oxidative and inflammatory processes. The main concerns that arise from the evaluation of the preventive/therapeutic effects of curcumin are, first of all, the still small number of randomized placebo-control studies available; in addition, small sample sizes have generally been considered, and different protocols and different formulations as well as different routes of administration of curcumin have been used. Thus, it is quite difficult to compare the results and to provide a standard protocol for the use of this promising natural compound. For these reasons, and taking in account the growing use of curcumin by the general population, further investigations to confirm and expand current findings are mandatory and research on curcumin and its effects on human health have to be fostered and promoted.
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spelling doab-20.500.12854ir-966902024-03-31T13:09:54Z Dietary Curcumin and Health Effects Masella, Roberta Cirulli, Francesca curcumin glycogen synthase kinase-3 insulin resistance Islet amyloid polypeptide type 2 diabetes mellitus inflammatory bowel disease proctocolitis turmeric complementary therapies phytotherapy gut microbiota polyphenols health fish oil mood subjective memory complaints APOE4 randomized controlled trial pregnancy pregnancy complications postpartum depression fetal development preterm birth adverse effects bioactive nutraceutical nutriepigenomics DNA methylation breast cancer chemoprevention curcuma type 2 diabetes dyslipidemia meta-analysis randomized control trial glioblastoma anticancer molecular signaling mechanism obesity inflammation adipose tissue aging brain cognition bioavailability oxidative stress antioxidant microbiota micelles apoptosis comet assay genotoxicity senolytics n/a thema EDItEUR::M Medicine and Nursing The Special Issue provides twelve contributions, of which three original articles, seven narrative reviews, one systematic review, and one meta-analysis that, altogether, offer a multifaceted and multidisciplinary overview that allows to draw a picture as intriguing and fascinating as possible on the benefits of curcumin and also to suggest potential fields of activities still to be explored. Among the biological activities exerted by curcumin, the anti-oxidative and anti-inflammatory properties reported in many studies make it a potential effective tool in preventing and counteracting chronic-degenerative diseases, very often associated with obesity and aging, such as cardiovascular diseases, T2D, metabolic dysfunctions, neurodegenerative diseases, and cancer, all of them characterized by the presence of oxidative and inflammatory processes. The main concerns that arise from the evaluation of the preventive/therapeutic effects of curcumin are, first of all, the still small number of randomized placebo-control studies available; in addition, small sample sizes have generally been considered, and different protocols and different formulations as well as different routes of administration of curcumin have been used. Thus, it is quite difficult to compare the results and to provide a standard protocol for the use of this promising natural compound. For these reasons, and taking in account the growing use of curcumin by the general population, further investigations to confirm and expand current findings are mandatory and research on curcumin and its effects on human health have to be fostered and promoted. 2023-02-02T16:38:41Z 2023-02-02T16:38:41Z 2023 book ONIX_20230202_9783036560878_91 9783036560878 9783036560885 https://directory.doabooks.org/handle/20.500.12854/96690 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6635 https://mdpi.com/books/pdfview/book/6635 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-6088-5 10.3390/books978-3-0365-6088-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036560878 9783036560885 208 Basel open access
spellingShingle curcumin
glycogen synthase kinase-3
insulin resistance
Islet amyloid polypeptide
type 2 diabetes mellitus
inflammatory bowel disease
proctocolitis
turmeric
complementary therapies
phytotherapy
gut microbiota
polyphenols
health
fish oil
mood
subjective memory complaints
APOE4
randomized controlled trial
pregnancy
pregnancy complications
postpartum depression
fetal development
preterm birth
adverse effects
bioactive nutraceutical
nutriepigenomics
DNA methylation
breast cancer
chemoprevention
curcuma
type 2 diabetes
dyslipidemia
meta-analysis
randomized control trial
glioblastoma
anticancer
molecular signaling mechanism
obesity
inflammation
adipose tissue
aging
brain
cognition
bioavailability
oxidative stress
antioxidant
microbiota
micelles
apoptosis
comet assay
genotoxicity
senolytics
n/a
thema EDItEUR::M Medicine and Nursing
Dietary Curcumin and Health Effects
title Dietary Curcumin and Health Effects
title_full Dietary Curcumin and Health Effects
title_fullStr Dietary Curcumin and Health Effects
title_full_unstemmed Dietary Curcumin and Health Effects
title_short Dietary Curcumin and Health Effects
title_sort dietary curcumin and health effects
topic curcumin
glycogen synthase kinase-3
insulin resistance
Islet amyloid polypeptide
type 2 diabetes mellitus
inflammatory bowel disease
proctocolitis
turmeric
complementary therapies
phytotherapy
gut microbiota
polyphenols
health
fish oil
mood
subjective memory complaints
APOE4
randomized controlled trial
pregnancy
pregnancy complications
postpartum depression
fetal development
preterm birth
adverse effects
bioactive nutraceutical
nutriepigenomics
DNA methylation
breast cancer
chemoprevention
curcuma
type 2 diabetes
dyslipidemia
meta-analysis
randomized control trial
glioblastoma
anticancer
molecular signaling mechanism
obesity
inflammation
adipose tissue
aging
brain
cognition
bioavailability
oxidative stress
antioxidant
microbiota
micelles
apoptosis
comet assay
genotoxicity
senolytics
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet curcumin
glycogen synthase kinase-3
insulin resistance
Islet amyloid polypeptide
type 2 diabetes mellitus
inflammatory bowel disease
proctocolitis
turmeric
complementary therapies
phytotherapy
gut microbiota
polyphenols
health
fish oil
mood
subjective memory complaints
APOE4
randomized controlled trial
pregnancy
pregnancy complications
postpartum depression
fetal development
preterm birth
adverse effects
bioactive nutraceutical
nutriepigenomics
DNA methylation
breast cancer
chemoprevention
curcuma
type 2 diabetes
dyslipidemia
meta-analysis
randomized control trial
glioblastoma
anticancer
molecular signaling mechanism
obesity
inflammation
adipose tissue
aging
brain
cognition
bioavailability
oxidative stress
antioxidant
microbiota
micelles
apoptosis
comet assay
genotoxicity
senolytics
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20230202_9783036560878_91