p53
p53 is a protein that plays an important role in the regulation of cell division and thereby offers protection to the cell against malignant transformation. This is the most well-studied and most appreciated role of p53, due to which the protein is famously known as the “guardian of the genome.” It...
Gardado en:
| Formato: | Online |
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| Idioma: | inglés |
| Publicado: |
IntechOpen
2023
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| Subjects: | |
| Acceso en liña: | ONIX_20230215_9781839681462_141 |
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| _version_ | 1869530061843988480 |
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| collection | Directory of Open Access Books |
| description | p53 is a protein that plays an important role in the regulation of cell division and thereby offers protection to the cell against malignant transformation. This is the most well-studied and most appreciated role of p53, due to which the protein is famously known as the “guardian of the genome.” It is the most studied protein in all forms of cancer research, with much of this research investigating p53’s role in tumor suppression. However, research has also shown that p53 plays a role in a wide range of other cellular functions, like serving as a biomarker for environmental pollution. Even as a tumor suppressor and transcription factor, many aspects of p53 function are still obscure, and research in the field is continually attempting to shed light on these functions. This book examines and discusses the myriad roles of p53 and different aspects of its functions. Chapters examine p53 in cancer prevention, DNA repair, gene regulation, and more. |
| format | Online |
| id | doab-20.500.12854ir-97101 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-971012024-03-31T22:45:29Z p53 Anwar, Mumtaz Farooq, Zeenat Tauseef, Mohammad Avin Balaji Ragunathrao, Vijay Pre-clinical medicine: basic sciences thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics p53 is a protein that plays an important role in the regulation of cell division and thereby offers protection to the cell against malignant transformation. This is the most well-studied and most appreciated role of p53, due to which the protein is famously known as the “guardian of the genome.” It is the most studied protein in all forms of cancer research, with much of this research investigating p53’s role in tumor suppression. However, research has also shown that p53 plays a role in a wide range of other cellular functions, like serving as a biomarker for environmental pollution. Even as a tumor suppressor and transcription factor, many aspects of p53 function are still obscure, and research in the field is continually attempting to shed light on these functions. This book examines and discusses the myriad roles of p53 and different aspects of its functions. Chapters examine p53 in cancer prevention, DNA repair, gene regulation, and more. 2023-02-15T14:41:11Z 2023-02-15T14:41:11Z 2022 book ONIX_20230215_9781839681462_141 9781839681462 9781839681455 9781839681479 https://directory.doabooks.org/handle/20.500.12854/97101 eng image/jpeg n/a https://www.intechopen.com/books/10246 https://mts.intechopen.com/storage/books/10246/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.91087 10.5772/intechopen.91087 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781839681462 9781839681455 9781839681479 IntechOpen 134 open access |
| spellingShingle | Pre-clinical medicine: basic sciences thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics p53 |
| title | p53 |
| title_full | p53 |
| title_fullStr | p53 |
| title_full_unstemmed | p53 |
| title_short | p53 |
| title_sort | p53 |
| topic | Pre-clinical medicine: basic sciences thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics |
| topic_facet | Pre-clinical medicine: basic sciences thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics |
| url | ONIX_20230215_9781839681462_141 |