From Pathophysiology to Treatment of Huntington's Disease

Huntington’s Disease (HD) is a progressive neurodegenerative disease leading to a variety of neurological and psychiatric symptoms such as chorea, parkinsonism, oculomotor symptoms, cognitive decline, depression, suicidal ideation, and psychosis. Currently, only symptomatic treatment is available. I...

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Ngôn ngữ:Tiếng Anh
Được phát hành: IntechOpen 2023
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collection Directory of Open Access Books
description Huntington’s Disease (HD) is a progressive neurodegenerative disease leading to a variety of neurological and psychiatric symptoms such as chorea, parkinsonism, oculomotor symptoms, cognitive decline, depression, suicidal ideation, and psychosis. Currently, only symptomatic treatment is available. In recent years, there has been a growing number of publications regarding pathophysiology, disease biomarkers, and possible avenues for causal therapy of HD. This book presents an overview of the most important research updates in the pathophysiology and treatment of HD, with particular reference to advances in HD neuropathology, neuroimaging, and biomarkers of HD. We also summarize possible new therapeutic targets, including cannabis-based medicine, cellular, and cell-free therapeutics. Importantly, researchers from different regions of the world have contributed to this volume as we wanted to create a balanced, inclusive, and interdisciplinary review of the topics. We hope that with this book readers will be offered a compact summary of up-to-date trends in HD research which, ultimately, will enable better diagnosis and treatment for HD patients.
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spelling doab-20.500.12854ir-971792024-04-01T14:15:20Z From Pathophysiology to Treatment of Huntington's Disease Szejko, Natalia Clinical & internal medicine thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology Huntington’s Disease (HD) is a progressive neurodegenerative disease leading to a variety of neurological and psychiatric symptoms such as chorea, parkinsonism, oculomotor symptoms, cognitive decline, depression, suicidal ideation, and psychosis. Currently, only symptomatic treatment is available. In recent years, there has been a growing number of publications regarding pathophysiology, disease biomarkers, and possible avenues for causal therapy of HD. This book presents an overview of the most important research updates in the pathophysiology and treatment of HD, with particular reference to advances in HD neuropathology, neuroimaging, and biomarkers of HD. We also summarize possible new therapeutic targets, including cannabis-based medicine, cellular, and cell-free therapeutics. Importantly, researchers from different regions of the world have contributed to this volume as we wanted to create a balanced, inclusive, and interdisciplinary review of the topics. We hope that with this book readers will be offered a compact summary of up-to-date trends in HD research which, ultimately, will enable better diagnosis and treatment for HD patients. 2023-02-15T14:46:25Z 2023-02-15T14:46:25Z 2022 book ONIX_20230215_9781803554273_218 9781803554273 9781803554266 9781803554280 https://directory.doabooks.org/handle/20.500.12854/97179 eng image/jpeg n/a https://www.intechopen.com/books/10783 https://mts.intechopen.com/storage/books/10783/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.94806 10.5772/intechopen.94806 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781803554273 9781803554266 9781803554280 IntechOpen 170 open access
spellingShingle Clinical & internal medicine
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
From Pathophysiology to Treatment of Huntington's Disease
title From Pathophysiology to Treatment of Huntington's Disease
title_full From Pathophysiology to Treatment of Huntington's Disease
title_fullStr From Pathophysiology to Treatment of Huntington's Disease
title_full_unstemmed From Pathophysiology to Treatment of Huntington's Disease
title_short From Pathophysiology to Treatment of Huntington's Disease
title_sort from pathophysiology to treatment of huntington s disease
topic Clinical & internal medicine
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
topic_facet Clinical & internal medicine
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
url ONIX_20230215_9781803554273_218