Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis that develops in the absence of competing for liver disease etiologies such as alcohol consumption, monogenic hereditary conditions, or iatrogenic causes. The pathogenesis of NAFLD is multifactorial and its understanding...
Gorde:
| Formatua: | Online |
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| Hizkuntza: | ingelesa |
| Argitaratua: |
IntechOpen
2023
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| Gaiak: | |
| Sarrera elektronikoa: | ONIX_20230215_9781839680915_378 |
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| _version_ | 1869515667089129472 |
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| collection | Directory of Open Access Books |
| description | Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis that develops in the absence of competing for liver disease etiologies such as alcohol consumption, monogenic hereditary conditions, or iatrogenic causes. The pathogenesis of NAFLD is multifactorial and its understanding is still incomplete. Although knowledge of the cellular and molecular mechanisms underlying disease development and progression has grown significantly in recent years, the exact contribution of environmental and genetic factors as well as that of extrahepatic and intrahepatic events in determining the disease phenotype remains ill defined. This book discusses topics highly correlated with NAFLD such as the regulation of iron metabolism, the role of the enzyme heparanase in liver steatosis, transcriptional regulation by ERR and its role in pathogenesis, hepatic lipid homeostasis, therapeutic approaches to NAFLD, and pathogenesis and significance of HDL as a molecular modifier in NAFLD. |
| format | Online |
| id | doab-20.500.12854ir-97340 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-973402024-03-31T22:44:24Z Non-alcoholic Fatty Liver Disease Kang, Ju-Seop Clinical & internal medicine thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis that develops in the absence of competing for liver disease etiologies such as alcohol consumption, monogenic hereditary conditions, or iatrogenic causes. The pathogenesis of NAFLD is multifactorial and its understanding is still incomplete. Although knowledge of the cellular and molecular mechanisms underlying disease development and progression has grown significantly in recent years, the exact contribution of environmental and genetic factors as well as that of extrahepatic and intrahepatic events in determining the disease phenotype remains ill defined. This book discusses topics highly correlated with NAFLD such as the regulation of iron metabolism, the role of the enzyme heparanase in liver steatosis, transcriptional regulation by ERR and its role in pathogenesis, hepatic lipid homeostasis, therapeutic approaches to NAFLD, and pathogenesis and significance of HDL as a molecular modifier in NAFLD. 2023-02-15T14:58:48Z 2023-02-15T14:58:48Z 2023 book ONIX_20230215_9781839680915_378 9781839680915 9781839680908 9781839681028 https://directory.doabooks.org/handle/20.500.12854/97340 eng image/jpeg n/a https://www.intechopen.com/books/11716 https://mts.intechopen.com/storage/books/11716/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.100998 10.5772/intechopen.100998 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781839680915 9781839680908 9781839681028 IntechOpen 156 open access |
| spellingShingle | Clinical & internal medicine thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology Non-alcoholic Fatty Liver Disease |
| title | Non-alcoholic Fatty Liver Disease |
| title_full | Non-alcoholic Fatty Liver Disease |
| title_fullStr | Non-alcoholic Fatty Liver Disease |
| title_full_unstemmed | Non-alcoholic Fatty Liver Disease |
| title_short | Non-alcoholic Fatty Liver Disease |
| title_sort | non alcoholic fatty liver disease |
| topic | Clinical & internal medicine thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology |
| topic_facet | Clinical & internal medicine thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology |
| url | ONIX_20230215_9781839680915_378 |