Human Papillomavirus and Head and Neck Cancer
In the study of head and neck squamous cell carcinoma (HNSCC), we know that virally induced malignancies behave differently than those generated through other carcinogenic mechanisms. This paradigm extends into differences in tumor growth, treatment response and resistance, as well as invasion and m...
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| Format: | Online |
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| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Online pristup: | ONIX_20230307_9783036567051_58 |
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| _version_ | 1869527024617390080 |
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| collection | Directory of Open Access Books |
| description | In the study of head and neck squamous cell carcinoma (HNSCC), we know that virally induced malignancies behave differently than those generated through other carcinogenic mechanisms. This paradigm extends into differences in tumor growth, treatment response and resistance, as well as invasion and metastasis. The inability to correctly diagnose and appropriately treat HNSCC at early stages has contributed to reduced survival for HNSCC patients, particularly those with HPV-negative disease. The examination of the molecular differences between HPV-positive and HPV-negative HNSCC will provide support for early diagnostic markers and guide appropriate treatment selection to improve patient care and survival.This Special Issue highlights current research efforts to understand the evolving contribution of human papillomavirus in HNSCC. |
| format | Online |
| id | doab-20.500.12854ir-98048 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-980482024-04-09T23:15:36Z Human Papillomavirus and Head and Neck Cancer Walline, Heather head and neck cancer human papillomavirus oropharyngeal cancer virus-related cancers human papillomavirus diagnosis sinonasal squamous cell carcinoma prevalence detection method anatomic subsite photodynamic therapy ER/mitochondrial photosensitizer paraptosis apoptosis autophagy HPV OPSCC tonsillar cancer survival OS DFS p16 recurrence cancer subtypes gene expression oropharynx HPV integration immune response keratinization TATI Human Papillomavirus (HPV) immune status hematological parameters radiotherapy oropharyngeal squamous cell carcinoma DNA methylation transposable elements overall survival head and neck squamous cell carcinoma extracellular vesicle proteomic oropharyngeal cancer (OPC) human papillomavirus (HPV) cancer stem cells (CSCs) CSC markers prognosis tumor heterogeneity positron emission tomography diffusion-weighted dynamic contrast-enhanced kinetic modeling fast exchange regime model community detection algorithm spin-glass model high-risk human papillomaviruses head and neck squamous cell carcinomas viral DNA integration PCR DIPS-PCR APOT-PCR WGS WES capture-based assay RNASeq FISH consequences of HPV integration p53 cancer glycolysis oxidative phosphorylation metabolism biomarkers staging TNM prognostic T regulatory lymphocytes FoxP3 Langerhans cells CD1a immune cells thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues In the study of head and neck squamous cell carcinoma (HNSCC), we know that virally induced malignancies behave differently than those generated through other carcinogenic mechanisms. This paradigm extends into differences in tumor growth, treatment response and resistance, as well as invasion and metastasis. The inability to correctly diagnose and appropriately treat HNSCC at early stages has contributed to reduced survival for HNSCC patients, particularly those with HPV-negative disease. The examination of the molecular differences between HPV-positive and HPV-negative HNSCC will provide support for early diagnostic markers and guide appropriate treatment selection to improve patient care and survival.This Special Issue highlights current research efforts to understand the evolving contribution of human papillomavirus in HNSCC. 2023-03-07T16:31:03Z 2023-03-07T16:31:03Z 2023 book ONIX_20230307_9783036567051_58 9783036567051 9783036567044 https://directory.doabooks.org/handle/20.500.12854/98048 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/6794 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-6704-4 10.3390/books978-3-0365-6704-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036567051 9783036567044 268 Basel open access |
| spellingShingle | head and neck cancer human papillomavirus oropharyngeal cancer virus-related cancers human papillomavirus diagnosis sinonasal squamous cell carcinoma prevalence detection method anatomic subsite photodynamic therapy ER/mitochondrial photosensitizer paraptosis apoptosis autophagy HPV OPSCC tonsillar cancer survival OS DFS p16 recurrence cancer subtypes gene expression oropharynx HPV integration immune response keratinization TATI Human Papillomavirus (HPV) immune status hematological parameters radiotherapy oropharyngeal squamous cell carcinoma DNA methylation transposable elements overall survival head and neck squamous cell carcinoma extracellular vesicle proteomic oropharyngeal cancer (OPC) human papillomavirus (HPV) cancer stem cells (CSCs) CSC markers prognosis tumor heterogeneity positron emission tomography diffusion-weighted dynamic contrast-enhanced kinetic modeling fast exchange regime model community detection algorithm spin-glass model high-risk human papillomaviruses head and neck squamous cell carcinomas viral DNA integration PCR DIPS-PCR APOT-PCR WGS WES capture-based assay RNASeq FISH consequences of HPV integration p53 cancer glycolysis oxidative phosphorylation metabolism biomarkers staging TNM prognostic T regulatory lymphocytes FoxP3 Langerhans cells CD1a immune cells thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues Human Papillomavirus and Head and Neck Cancer |
| title | Human Papillomavirus and Head and Neck Cancer |
| title_full | Human Papillomavirus and Head and Neck Cancer |
| title_fullStr | Human Papillomavirus and Head and Neck Cancer |
| title_full_unstemmed | Human Papillomavirus and Head and Neck Cancer |
| title_short | Human Papillomavirus and Head and Neck Cancer |
| title_sort | human papillomavirus and head and neck cancer |
| topic | head and neck cancer human papillomavirus oropharyngeal cancer virus-related cancers human papillomavirus diagnosis sinonasal squamous cell carcinoma prevalence detection method anatomic subsite photodynamic therapy ER/mitochondrial photosensitizer paraptosis apoptosis autophagy HPV OPSCC tonsillar cancer survival OS DFS p16 recurrence cancer subtypes gene expression oropharynx HPV integration immune response keratinization TATI Human Papillomavirus (HPV) immune status hematological parameters radiotherapy oropharyngeal squamous cell carcinoma DNA methylation transposable elements overall survival head and neck squamous cell carcinoma extracellular vesicle proteomic oropharyngeal cancer (OPC) human papillomavirus (HPV) cancer stem cells (CSCs) CSC markers prognosis tumor heterogeneity positron emission tomography diffusion-weighted dynamic contrast-enhanced kinetic modeling fast exchange regime model community detection algorithm spin-glass model high-risk human papillomaviruses head and neck squamous cell carcinomas viral DNA integration PCR DIPS-PCR APOT-PCR WGS WES capture-based assay RNASeq FISH consequences of HPV integration p53 cancer glycolysis oxidative phosphorylation metabolism biomarkers staging TNM prognostic T regulatory lymphocytes FoxP3 Langerhans cells CD1a immune cells thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| topic_facet | head and neck cancer human papillomavirus oropharyngeal cancer virus-related cancers human papillomavirus diagnosis sinonasal squamous cell carcinoma prevalence detection method anatomic subsite photodynamic therapy ER/mitochondrial photosensitizer paraptosis apoptosis autophagy HPV OPSCC tonsillar cancer survival OS DFS p16 recurrence cancer subtypes gene expression oropharynx HPV integration immune response keratinization TATI Human Papillomavirus (HPV) immune status hematological parameters radiotherapy oropharyngeal squamous cell carcinoma DNA methylation transposable elements overall survival head and neck squamous cell carcinoma extracellular vesicle proteomic oropharyngeal cancer (OPC) human papillomavirus (HPV) cancer stem cells (CSCs) CSC markers prognosis tumor heterogeneity positron emission tomography diffusion-weighted dynamic contrast-enhanced kinetic modeling fast exchange regime model community detection algorithm spin-glass model high-risk human papillomaviruses head and neck squamous cell carcinomas viral DNA integration PCR DIPS-PCR APOT-PCR WGS WES capture-based assay RNASeq FISH consequences of HPV integration p53 cancer glycolysis oxidative phosphorylation metabolism biomarkers staging TNM prognostic T regulatory lymphocytes FoxP3 Langerhans cells CD1a immune cells thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| url | ONIX_20230307_9783036567051_58 |