Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective
For centuries, nature has been an inspirational source for the discovery of drugs used in modern medicine. Nowadays, natural-based treatments continue to be employed for primary health care, particularly playing a significant role in folk medicine. In addition, we are currently observing an increasi...
Tallennettuna:
| Aineistotyyppi: | Online |
|---|---|
| Kieli: | englanti |
| Julkaistu: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Aiheet: | |
| Linkit: | ONIX_20230405_9783036568119_77 |
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| _version_ | 1869518438000492544 |
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| collection | Directory of Open Access Books |
| description | For centuries, nature has been an inspirational source for the discovery of drugs used in modern medicine. Nowadays, natural-based treatments continue to be employed for primary health care, particularly playing a significant role in folk medicine. In addition, we are currently observing an increasing use of natural-products-based supplements from botanical and marine sources, making their standardization and scientific validation a priority to guarantee the safety of these products. Natural products and/or synthetic derivatives using their novel structures have also been of utmost importance in drug discovery and development in several clinical areas. After a period of discreditation and reduced investment, we are now witnessing a renewed interest from the pharmaceutical industry and scientific community due to the urgent need to develop new drugs. This reprint comprises 11 original and 6 review articles dedicated to plant and marine natural products research, contributing to the scientific validation of their use and opening new perspectives in drug discovery |
| format | Online |
| id | doab-20.500.12854ir-98798 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-987982024-03-28T03:32:51Z Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective Duarte, Noelia propyl-propane-thiosulfinate propyl-propane-thiosulfonate antibacterial activity antifungal activity vapor mycosporines mycosporine-like amino acids (MAAs) mass spectrometry database photoprotective compounds UV-absorbing compounds melatonin endoplasmic reticulum stress diabesity kidney cellulite essential oil monoterpenes Thai herbal compress adipogenesis lipolysis vasorelaxation Asphodelus ramosus root-tubers inulin fructans fructooligosaccharide alkaline extraction high-performance thin layer chromatography NMR spectroscopy 2D NMR analyses infrared spectroscopy isofuranodiene Smyrnium olusatrum L. ischemic stroke NF-ĸB IL-1β TNF-α Plectranthus royleanone 7α-acetoxy-6β-hydroxyroyleanone ent-abietane antitumoral activity antimicrobial activity antioxidant Euphorbia flavonoids pharmacological activities structure–activity relationship Sambucus nigra L. ethosomes collagenase inhibition skin compatibility anthocyanins antioxidants dietary source bioavailability biological activity biosynthesis Posidonia oceanica autophagy lipid accumulation NAFLD herbal medicine amphotericin B candidiasis gel Bursera graveolens topical treatment linarin chemotaxonomy phytochemistry bioactivities (−)-usnic acid evernic acid salazinic acid secondary metabolites lichen extracts Garcinia indica kokum wild mangosteen pharmacological activity terpenoids Trypanosoma human African trypanosomiasis sleeping disease human American trypanosomiasis Chagas disease anticancer activity cytotoxicity Hymenocardia acida nanoencapsulation nanoparticle plant extract PLGA n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry For centuries, nature has been an inspirational source for the discovery of drugs used in modern medicine. Nowadays, natural-based treatments continue to be employed for primary health care, particularly playing a significant role in folk medicine. In addition, we are currently observing an increasing use of natural-products-based supplements from botanical and marine sources, making their standardization and scientific validation a priority to guarantee the safety of these products. Natural products and/or synthetic derivatives using their novel structures have also been of utmost importance in drug discovery and development in several clinical areas. After a period of discreditation and reduced investment, we are now witnessing a renewed interest from the pharmaceutical industry and scientific community due to the urgent need to develop new drugs. This reprint comprises 11 original and 6 review articles dedicated to plant and marine natural products research, contributing to the scientific validation of their use and opening new perspectives in drug discovery 2023-04-05T12:51:42Z 2023-04-05T12:51:42Z 2023 book ONIX_20230405_9783036568119_77 9783036568119 9783036568102 https://directory.doabooks.org/handle/20.500.12854/98798 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6834 https://mdpi.com/books/pdfview/book/6834 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-6810-2 10.3390/books978-3-0365-6810-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036568119 9783036568102 346 Basel open access |
| spellingShingle | propyl-propane-thiosulfinate propyl-propane-thiosulfonate antibacterial activity antifungal activity vapor mycosporines mycosporine-like amino acids (MAAs) mass spectrometry database photoprotective compounds UV-absorbing compounds melatonin endoplasmic reticulum stress diabesity kidney cellulite essential oil monoterpenes Thai herbal compress adipogenesis lipolysis vasorelaxation Asphodelus ramosus root-tubers inulin fructans fructooligosaccharide alkaline extraction high-performance thin layer chromatography NMR spectroscopy 2D NMR analyses infrared spectroscopy isofuranodiene Smyrnium olusatrum L. ischemic stroke NF-ĸB IL-1β TNF-α Plectranthus royleanone 7α-acetoxy-6β-hydroxyroyleanone ent-abietane antitumoral activity antimicrobial activity antioxidant Euphorbia flavonoids pharmacological activities structure–activity relationship Sambucus nigra L. ethosomes collagenase inhibition skin compatibility anthocyanins antioxidants dietary source bioavailability biological activity biosynthesis Posidonia oceanica autophagy lipid accumulation NAFLD herbal medicine amphotericin B candidiasis gel Bursera graveolens topical treatment linarin chemotaxonomy phytochemistry bioactivities (−)-usnic acid evernic acid salazinic acid secondary metabolites lichen extracts Garcinia indica kokum wild mangosteen pharmacological activity terpenoids Trypanosoma human African trypanosomiasis sleeping disease human American trypanosomiasis Chagas disease anticancer activity cytotoxicity Hymenocardia acida nanoencapsulation nanoparticle plant extract PLGA n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective |
| title | Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective |
| title_full | Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective |
| title_fullStr | Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective |
| title_full_unstemmed | Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective |
| title_short | Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective |
| title_sort | plant and marine derived natural product research in drug discovery strengths and perspective |
| topic | propyl-propane-thiosulfinate propyl-propane-thiosulfonate antibacterial activity antifungal activity vapor mycosporines mycosporine-like amino acids (MAAs) mass spectrometry database photoprotective compounds UV-absorbing compounds melatonin endoplasmic reticulum stress diabesity kidney cellulite essential oil monoterpenes Thai herbal compress adipogenesis lipolysis vasorelaxation Asphodelus ramosus root-tubers inulin fructans fructooligosaccharide alkaline extraction high-performance thin layer chromatography NMR spectroscopy 2D NMR analyses infrared spectroscopy isofuranodiene Smyrnium olusatrum L. ischemic stroke NF-ĸB IL-1β TNF-α Plectranthus royleanone 7α-acetoxy-6β-hydroxyroyleanone ent-abietane antitumoral activity antimicrobial activity antioxidant Euphorbia flavonoids pharmacological activities structure–activity relationship Sambucus nigra L. ethosomes collagenase inhibition skin compatibility anthocyanins antioxidants dietary source bioavailability biological activity biosynthesis Posidonia oceanica autophagy lipid accumulation NAFLD herbal medicine amphotericin B candidiasis gel Bursera graveolens topical treatment linarin chemotaxonomy phytochemistry bioactivities (−)-usnic acid evernic acid salazinic acid secondary metabolites lichen extracts Garcinia indica kokum wild mangosteen pharmacological activity terpenoids Trypanosoma human African trypanosomiasis sleeping disease human American trypanosomiasis Chagas disease anticancer activity cytotoxicity Hymenocardia acida nanoencapsulation nanoparticle plant extract PLGA n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | propyl-propane-thiosulfinate propyl-propane-thiosulfonate antibacterial activity antifungal activity vapor mycosporines mycosporine-like amino acids (MAAs) mass spectrometry database photoprotective compounds UV-absorbing compounds melatonin endoplasmic reticulum stress diabesity kidney cellulite essential oil monoterpenes Thai herbal compress adipogenesis lipolysis vasorelaxation Asphodelus ramosus root-tubers inulin fructans fructooligosaccharide alkaline extraction high-performance thin layer chromatography NMR spectroscopy 2D NMR analyses infrared spectroscopy isofuranodiene Smyrnium olusatrum L. ischemic stroke NF-ĸB IL-1β TNF-α Plectranthus royleanone 7α-acetoxy-6β-hydroxyroyleanone ent-abietane antitumoral activity antimicrobial activity antioxidant Euphorbia flavonoids pharmacological activities structure–activity relationship Sambucus nigra L. ethosomes collagenase inhibition skin compatibility anthocyanins antioxidants dietary source bioavailability biological activity biosynthesis Posidonia oceanica autophagy lipid accumulation NAFLD herbal medicine amphotericin B candidiasis gel Bursera graveolens topical treatment linarin chemotaxonomy phytochemistry bioactivities (−)-usnic acid evernic acid salazinic acid secondary metabolites lichen extracts Garcinia indica kokum wild mangosteen pharmacological activity terpenoids Trypanosoma human African trypanosomiasis sleeping disease human American trypanosomiasis Chagas disease anticancer activity cytotoxicity Hymenocardia acida nanoencapsulation nanoparticle plant extract PLGA n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | ONIX_20230405_9783036568119_77 |