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Clinical, Pathological, and Molecular Characteristics in Colorectal Cancer

Despite major medical advances in recent decades, colorectal cancer remains a major public health problem with significant unmet medical needs. This reprint presents new scientific and clinical data, and discusses the need to identify new theranostic biomarkers from tissue and fluid biopsies, to go...

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Enregistré dans:
Format: Online
Langue:anglais
Publié: MDPI - Multidisciplinary Digital Publishing Institute 2023
Sujets:
Snail transcription factor
extracellular vesicles
colon cancer
pre-metastatic niche
PD-L1
CMS
RAS mutations
colorectal cancer
liver metastases
surgery
resection
ablation
discoidin domain receptor
prognosis
event free survival
survival
chemokine
ACKR3
metastasis
microenvironment
signaling pathways
epigenetics
therapy
resistance
lung metastases
protein biomarker
dual expression
early recurrence
poor prognosis
precision medicine
ERBB2
HER-2
Lynch Syndrome
mismatch repair proteins
genome-wide association study
Mendelian randomization
polygenic risk scores
liquid biopsy
rare cell
circulating tumor cells
oncosomes
heterogeneity
multi-assay
high-definition single-cell assay
colonic neoplasms
chemotherapy
adjuvant
tumor budding
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Accès en ligne:ONIX_20230405_9783036568379_157
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Résumé:Despite major medical advances in recent decades, colorectal cancer remains a major public health problem with significant unmet medical needs. This reprint presents new scientific and clinical data, and discusses the need to identify new theranostic biomarkers from tissue and fluid biopsies, to go further in terms of personalised medicine and thus overcome current limitations.

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