Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment
Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective tr...
保存先:
| フォーマット: | Online |
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| 言語: | 英語 |
| 出版事項: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| 主題: | |
| オンライン･アクセス: | ONIX_20230405_9783036570419_203 |
| タグ: |
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| _version_ | 1869515235220520960 |
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| collection | Directory of Open Access Books |
| description | Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy. |
| format | Online |
| id | doab-20.500.12854ir-98924 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-989242024-03-31T13:08:08Z Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment Zhang, Huijie graphene quantum dot targeted drug delivery photothermal therapy chemo-therapy polymeric prodrug theranostic nanocomplex pH-triggering releasing magnetic targeting magnetic hyperthermia magnetic resonance imaging docetaxel adenosine receptors PLGA nanoparticles lung cancer Notch signaling RBPJ protein drug repurposing fidaxomicin acarbose schaftoside breast cancer experimental skin cancer entrapment efficacy ethosomes metformin in vitro permeation zeta potential sesamol albumin nanoparticles doxorubicin oxidative stress antioxidants tumor-derived membrane vesicles cancer therapy tumor vaccine personalized immunotherapy low-density lipoprotein nanoparticle tumor microenvironment-responsive magnetic nanofluid improved magnetic resonance imaging neutral-responsive Fenton reaction enhanced chemodynamic therapy brain targeting folate receptor glioma cancer erlotinib blood–brain barrier thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy. 2023-04-05T12:59:18Z 2023-04-05T12:59:18Z 2023 book ONIX_20230405_9783036570419_203 9783036570419 9783036570402 https://directory.doabooks.org/handle/20.500.12854/98924 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/6977 https://mdpi.com/books/pdfview/book/6977 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7040-2 10.3390/books978-3-0365-7040-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036570419 9783036570402 212 Basel open access |
| spellingShingle | graphene quantum dot targeted drug delivery photothermal therapy chemo-therapy polymeric prodrug theranostic nanocomplex pH-triggering releasing magnetic targeting magnetic hyperthermia magnetic resonance imaging docetaxel adenosine receptors PLGA nanoparticles lung cancer Notch signaling RBPJ protein drug repurposing fidaxomicin acarbose schaftoside breast cancer experimental skin cancer entrapment efficacy ethosomes metformin in vitro permeation zeta potential sesamol albumin nanoparticles doxorubicin oxidative stress antioxidants tumor-derived membrane vesicles cancer therapy tumor vaccine personalized immunotherapy low-density lipoprotein nanoparticle tumor microenvironment-responsive magnetic nanofluid improved magnetic resonance imaging neutral-responsive Fenton reaction enhanced chemodynamic therapy brain targeting folate receptor glioma cancer erlotinib blood–brain barrier thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment |
| title | Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment |
| title_full | Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment |
| title_fullStr | Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment |
| title_full_unstemmed | Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment |
| title_short | Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment |
| title_sort | recent progress of nanomedicine and targeted drug delivery for cancer treatment |
| topic | graphene quantum dot targeted drug delivery photothermal therapy chemo-therapy polymeric prodrug theranostic nanocomplex pH-triggering releasing magnetic targeting magnetic hyperthermia magnetic resonance imaging docetaxel adenosine receptors PLGA nanoparticles lung cancer Notch signaling RBPJ protein drug repurposing fidaxomicin acarbose schaftoside breast cancer experimental skin cancer entrapment efficacy ethosomes metformin in vitro permeation zeta potential sesamol albumin nanoparticles doxorubicin oxidative stress antioxidants tumor-derived membrane vesicles cancer therapy tumor vaccine personalized immunotherapy low-density lipoprotein nanoparticle tumor microenvironment-responsive magnetic nanofluid improved magnetic resonance imaging neutral-responsive Fenton reaction enhanced chemodynamic therapy brain targeting folate receptor glioma cancer erlotinib blood–brain barrier thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | graphene quantum dot targeted drug delivery photothermal therapy chemo-therapy polymeric prodrug theranostic nanocomplex pH-triggering releasing magnetic targeting magnetic hyperthermia magnetic resonance imaging docetaxel adenosine receptors PLGA nanoparticles lung cancer Notch signaling RBPJ protein drug repurposing fidaxomicin acarbose schaftoside breast cancer experimental skin cancer entrapment efficacy ethosomes metformin in vitro permeation zeta potential sesamol albumin nanoparticles doxorubicin oxidative stress antioxidants tumor-derived membrane vesicles cancer therapy tumor vaccine personalized immunotherapy low-density lipoprotein nanoparticle tumor microenvironment-responsive magnetic nanofluid improved magnetic resonance imaging neutral-responsive Fenton reaction enhanced chemodynamic therapy brain targeting folate receptor glioma cancer erlotinib blood–brain barrier thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | ONIX_20230405_9783036570419_203 |