Radiation Damage in Biomolecules and Cells

The papers collected in this Special Issue deal with the effects of ionizing radiation at molecular and cellular levels, as well as possible applications in medicine and radiation protection. In particular, some works analysed the early stages of the interaction between ionizing radiation and DNA fo...

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Detalhes bibliográficos
Formato:	Online
Idioma:	inglês
Publicado em:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:	glioblastoma multiforme proton therapy combined treatments gene signatures brain arteriovenous malformation endothelial cells ionizing radiation proteomics stereotactic radiosurgery vascular targeting DNA repair hypoxia modeling radiosensitizer Monte Carlo simulation Geant4/Geant4-DNA X-rays microdosimetry nanodosimetry DSB yield radiation track chemistry chemical track structure oxygen effect oxygen depletion ion beam therapy ROS superoxide anion Monte Carlo radiation transport complex DNA damage coupled with base damage modelling of DNA damage yields amino acid valine MeV ion irradiation radiolysis infrared absorption spectroscopy destruction cross section stopping power dependence carbon ions radiation-induced damage chromatin structure electron microscopy CLEM DNA and RNA cytochemistry Osmium ammine B ChromEMT DNA-specific staining high-dose ionizing radiation RNA-Seq differential gene expression DNA damage response triple-negative breast cancer CHK1 Rad51 direct and indirect damage DMSO radicals radical scavengers Glioblastoma DNA damage head-and-neck tumors ion beam radiotherapy relative biological effectiveness (RBE) RBE models protons Monte Carlo simulations embryo gastrulation preimplantation apoptosis glioblastoma stem cells metabolism MRS photon beams pencil beam scanning double scattering cell survival radiation doses repair mechanism translocation transition transversion ratio IR-induced variants SNVs InDels topological associating domains melatonin oxidative stress radioprotection reactive oxygen species vitamin D radiation biology radiation protection health effects epigenetics low dose radiation DNA methylation non-targeted effects triple-negative breast cancer (TNBC) xenograft mice microarray environmental radiation hibernation HIF-1 hypothermia radioresistance space travel FLASH proton beam therapy radiotherapy radiobiology n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Acesso em linha:	ONIX_20230511_9783036574875_144
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Radiation Damage in Biomolecules and Cells

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