Copertina

Liver Cancer

Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a num...

Descrizione completa

Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: IntechOpen 2023
Soggetti:
hepatocellular carcinoma
liver cirrhosis
inflammation
biomarkers
immunotherapy
gene expression
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Accesso online:ONIX_20230905_9781803564142_159
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
Riassunto:Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis.

Documenti analoghi