Liver Cancer
Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a num...
שמור ב:
| פורמט: | Online |
|---|---|
| שפה: | אנגלית |
| יצא לאור: |
IntechOpen
2023
|
| נושאים: | |
| גישה מקוונת: | ONIX_20230905_9781803564142_159 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|
| _version_ | 1869517346519908352 |
|---|---|
| collection | Directory of Open Access Books |
| description | Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis. |
| format | Online |
| id | doab-20.500.12854ir-113358 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1133582024-03-31T22:45:52Z Liver Cancer Feitelson, Mark Arzumanyan, Alla hepatocellular carcinoma liver cirrhosis inflammation biomarkers immunotherapy gene expression thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis. 2023-09-05T16:00:18Z 2023-09-05T16:00:18Z 2023 book ONIX_20230905_9781803564142_159 9781803564142 9781803564135 9781803564159 https://directory.doabooks.org/handle/20.500.12854/113358 eng image/jpeg n/a https://www.intechopen.com/books/11596 https://mts.intechopen.com/storage/books/11596/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.100845 10.5772/intechopen.100845 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781803564142 9781803564135 9781803564159 IntechOpen 146 open access |
| spellingShingle | hepatocellular carcinoma liver cirrhosis inflammation biomarkers immunotherapy gene expression thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Liver Cancer |
| title | Liver Cancer |
| title_full | Liver Cancer |
| title_fullStr | Liver Cancer |
| title_full_unstemmed | Liver Cancer |
| title_short | Liver Cancer |
| title_sort | liver cancer |
| topic | hepatocellular carcinoma liver cirrhosis inflammation biomarkers immunotherapy gene expression thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | hepatocellular carcinoma liver cirrhosis inflammation biomarkers immunotherapy gene expression thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20230905_9781803564142_159 |