Quantitative Structure-activity Relationship
The book, which is related to QSAR in sciences, is divided into five main chapters. The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of p...
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| Format: | Online |
|---|---|
| Jezik: | engleski |
| Izdano: |
IntechOpen
2023
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| Teme: | |
| Online pristup: | ONIX_20231201_9789535134107_587 |
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| _version_ | 1869519463241482240 |
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| collection | Directory of Open Access Books |
| description | The book, which is related to QSAR in sciences, is divided into five main chapters. The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of peptidic inhibitors that possessed a substrate transition-state analog and evaluating the structure-activity relationship of the designed inhibitors, based on docking and scoring, using the docking simulation software Molecular Operating Environment. The aim of the forth chapter is to develop structure-property relationships for the qualitative and quantitative prediction of the reverse-phase liquid chromatographic retention times of chlorogenic acids. The final chapter aims to determine the model of interactions between the natural compounds with anti-inflammatory molecular target by molecular docking analysis. |
| format | Online |
| id | doab-20.500.12854ir-129478 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1294782024-04-05T17:30:44Z Quantitative Structure-activity Relationship Kandemirli, Fatma alzheimer’s disease, molecular dynamics, anti-inflammatory, fractal dimension, natural compounds, coffee thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry The book, which is related to QSAR in sciences, is divided into five main chapters. The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of peptidic inhibitors that possessed a substrate transition-state analog and evaluating the structure-activity relationship of the designed inhibitors, based on docking and scoring, using the docking simulation software Molecular Operating Environment. The aim of the forth chapter is to develop structure-property relationships for the qualitative and quantitative prediction of the reverse-phase liquid chromatographic retention times of chlorogenic acids. The final chapter aims to determine the model of interactions between the natural compounds with anti-inflammatory molecular target by molecular docking analysis. 2023-12-01T15:29:48Z 2023-12-01T15:29:48Z 2017 book ONIX_20231201_9789535134107_587 9789535134107 9789535134091 9789535146803 https://directory.doabooks.org/handle/20.500.12854/129478 eng image/jpeg n/a https://www.intechopen.com/books/5843 https://mts.intechopen.com/storage/books/5843/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/65597 10.5772/65597 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535134107 9789535134091 9789535146803 IntechOpen 88 open access |
| spellingShingle | alzheimer’s disease, molecular dynamics, anti-inflammatory, fractal dimension, natural compounds, coffee thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Quantitative Structure-activity Relationship |
| title | Quantitative Structure-activity Relationship |
| title_full | Quantitative Structure-activity Relationship |
| title_fullStr | Quantitative Structure-activity Relationship |
| title_full_unstemmed | Quantitative Structure-activity Relationship |
| title_short | Quantitative Structure-activity Relationship |
| title_sort | quantitative structure activity relationship |
| topic | alzheimer’s disease, molecular dynamics, anti-inflammatory, fractal dimension, natural compounds, coffee thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | alzheimer’s disease, molecular dynamics, anti-inflammatory, fractal dimension, natural compounds, coffee thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20231201_9789535134107_587 |