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Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases

This Special Issue, titled "Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases", includes reports on new findings and topics of current interest in the topoisomerase field. Topics include structural, biochemical, and pharmacological studies and reviews for both eukaryotic...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2024
Fag:
zoliflodacin
quinolones
DNA gyrase
topoisomerase IV
ESKAPE
antibiotic
spiropyrimidinetrione
NBTI
gepotidacin
structure
mini
topoisomerase II
catalytic inhibitors
poisons
DNA
salicylate
cardiotoxicity
MD simulation
quinolone
quinolone resistance
water–metal ion bridge
gyrase
topoisomerase
DNA topoisomerase
DNA supercoiling
DNA relaxation
DNA decatenation
type IA topoisomerase
type IIA topoisomerase
structural biology
DNA topoisomerase I
supercoiling regulation
supercoiling homeostasis
nucleoid-associated proteins
topsoisomerase regulator
StaR
Z-DNA
topoisomerase IIα
topoII
GTP
bioinformatics
DNA topology
supercoil handedness
type II topoisomerase
DNA cleavage
thiosemicarbazone
antitumor
bis-thiosemicarbazone
novel bacterial topoisomerase inhibitor
Neisseria gonorrhoeae
n/a
anticancer
DNA damage
transcription
chromatin
TOP2
TOP2B
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online adgang:ONIX_20240514_9783036597010_7
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Summary:This Special Issue, titled "Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases", includes reports on new findings and topics of current interest in the topoisomerase field. Topics include structural, biochemical, and pharmacological studies and reviews for both eukaryotic and prokaryotic topoisomerases.

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