Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases
This Special Issue, titled "Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases", includes reports on new findings and topics of current interest in the topoisomerase field. Topics include structural, biochemical, and pharmacological studies and reviews for both eukaryotic...
محفوظ في:
| التنسيق: | Online |
|---|---|
| اللغة: | الإنجليزية |
| منشور في: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | ONIX_20240514_9783036597010_7 |
| الوسوم: |
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1869530195401113600 |
|---|---|
| collection | Directory of Open Access Books |
| description | This Special Issue, titled "Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases", includes reports on new findings and topics of current interest in the topoisomerase field. Topics include structural, biochemical, and pharmacological studies and reviews for both eukaryotic and prokaryotic topoisomerases. |
| format | Online |
| id | doab-20.500.12854ir-137403 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1374032024-05-14T12:56:17Z Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases Deweese, Joseph E. Osheroff, Neil zoliflodacin quinolones DNA gyrase topoisomerase IV ESKAPE antibiotic spiropyrimidinetrione NBTI gepotidacin structure mini topoisomerase II catalytic inhibitors poisons DNA salicylate cardiotoxicity MD simulation quinolone quinolone resistance water–metal ion bridge gyrase topoisomerase DNA topoisomerase DNA supercoiling DNA relaxation DNA decatenation type IA topoisomerase type IIA topoisomerase structural biology DNA topoisomerase I supercoiling regulation supercoiling homeostasis nucleoid-associated proteins topsoisomerase regulator StaR Z-DNA topoisomerase IIα topoII GTP bioinformatics DNA topology supercoil handedness type II topoisomerase DNA cleavage thiosemicarbazone antitumor bis-thiosemicarbazone novel bacterial topoisomerase inhibitor Neisseria gonorrhoeae n/a anticancer DNA damage transcription chromatin TOP2 TOP2B thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Special Issue, titled "Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases", includes reports on new findings and topics of current interest in the topoisomerase field. Topics include structural, biochemical, and pharmacological studies and reviews for both eukaryotic and prokaryotic topoisomerases. 2024-05-14T12:56:05Z 2024-05-14T12:56:05Z 2024 book ONIX_20240514_9783036597010_7 9783036597010 9783036597003 https://directory.doabooks.org/handle/20.500.12854/137403 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8556 https://mdpi.com/books/pdfview/book/8556 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9700-3 10.3390/books978-3-0365-9700-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036597010 9783036597003 186 open access |
| spellingShingle | zoliflodacin quinolones DNA gyrase topoisomerase IV ESKAPE antibiotic spiropyrimidinetrione NBTI gepotidacin structure mini topoisomerase II catalytic inhibitors poisons DNA salicylate cardiotoxicity MD simulation quinolone quinolone resistance water–metal ion bridge gyrase topoisomerase DNA topoisomerase DNA supercoiling DNA relaxation DNA decatenation type IA topoisomerase type IIA topoisomerase structural biology DNA topoisomerase I supercoiling regulation supercoiling homeostasis nucleoid-associated proteins topsoisomerase regulator StaR Z-DNA topoisomerase IIα topoII GTP bioinformatics DNA topology supercoil handedness type II topoisomerase DNA cleavage thiosemicarbazone antitumor bis-thiosemicarbazone novel bacterial topoisomerase inhibitor Neisseria gonorrhoeae n/a anticancer DNA damage transcription chromatin TOP2 TOP2B thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases |
| title | Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases |
| title_full | Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases |
| title_fullStr | Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases |
| title_full_unstemmed | Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases |
| title_short | Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases |
| title_sort | advances in structure function and molecular targeting of dna topoisomerases |
| topic | zoliflodacin quinolones DNA gyrase topoisomerase IV ESKAPE antibiotic spiropyrimidinetrione NBTI gepotidacin structure mini topoisomerase II catalytic inhibitors poisons DNA salicylate cardiotoxicity MD simulation quinolone quinolone resistance water–metal ion bridge gyrase topoisomerase DNA topoisomerase DNA supercoiling DNA relaxation DNA decatenation type IA topoisomerase type IIA topoisomerase structural biology DNA topoisomerase I supercoiling regulation supercoiling homeostasis nucleoid-associated proteins topsoisomerase regulator StaR Z-DNA topoisomerase IIα topoII GTP bioinformatics DNA topology supercoil handedness type II topoisomerase DNA cleavage thiosemicarbazone antitumor bis-thiosemicarbazone novel bacterial topoisomerase inhibitor Neisseria gonorrhoeae n/a anticancer DNA damage transcription chromatin TOP2 TOP2B thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | zoliflodacin quinolones DNA gyrase topoisomerase IV ESKAPE antibiotic spiropyrimidinetrione NBTI gepotidacin structure mini topoisomerase II catalytic inhibitors poisons DNA salicylate cardiotoxicity MD simulation quinolone quinolone resistance water–metal ion bridge gyrase topoisomerase DNA topoisomerase DNA supercoiling DNA relaxation DNA decatenation type IA topoisomerase type IIA topoisomerase structural biology DNA topoisomerase I supercoiling regulation supercoiling homeostasis nucleoid-associated proteins topsoisomerase regulator StaR Z-DNA topoisomerase IIα topoII GTP bioinformatics DNA topology supercoil handedness type II topoisomerase DNA cleavage thiosemicarbazone antitumor bis-thiosemicarbazone novel bacterial topoisomerase inhibitor Neisseria gonorrhoeae n/a anticancer DNA damage transcription chromatin TOP2 TOP2B thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20240514_9783036597010_7 |