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Carbohydrate-Based Drugs Discovery

Carbohydrates play an essential role in the organism and have many bioactivities. Carbohydrate-based drug discovery is an up-and-coming area of research in medicinal chemistry. Bioactive carbohydrates open up a new source for drug development. More than 170 carbohydrate-based drugs have been success...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2024
Fag:
hepatocellular carcinoma
metastasis
ASGPR
gene therapy
VEGF/VEGFR2 signaling pathway
breastfeeding women
saliva
sialic acids (Sia)
avian influenza virus (AIV)
glycoprotein
resin glycosides
macrocyclic natural glycolipids
ring-opened analogues
cytotoxicity
protein translocation
Sec61 translocon
molecular docking
LFG-Na
sea cucumber
Holothuria fuscopunctata
molecular weight
HPSEC-MALLS-RID
bioactivity assay
quality control
rhamnose
deoxythymidinediphosphate-L-rhamnose
guanosine diphosphate rhamnose
uridine diphosphate-rhamnose
rhamnosyltransferase
rhamnose biosynthesis
iminosugar
pyrrolidine
multivalent effect
glucosidase inhibitors
osteoarthritis
hyaluronic acid
hyaluronic acid oligosaccharide derivatives
ATDC5
lipopolysaccharide
active ingredients
polysaccharide purification
glucan
mannan
immunomodulator
heparin
applications of heparin
challenges of heparin therapy
glycosylation
Ferrier rearrangement
perfluorinated solvent
high stereoselectivity
reusability
aryl-C-glycoside
novel structures
bioactivity
synthesis
antibiotic
aminoglycoside
structural modification
structure–activity relationship
functional oligosaccharides
gut microbiota
intestinal barriers
intestinal diseases
2-deoxythioglycosides
silver triflate
stereoselective synthesis
glycals
anticancer
polysaccharides
drug delivery systems
nanomedicines
proteins
erythropoietin
monoclonal antibodies
amino alcohols
3-aminosugars
sulfamidates
deprotection
Kukhtin–Ramirez reaction
tumor-associated carbohydrate antigens
KH-1
fluoro-modification
tumor vaccine
thema EDItEUR::J Society and Social Sciences::JM Psychology::JMA Psychological theory, systems, schools and viewpoints
Online adgang:ONIX_20240514_9783725804320_381
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