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Recent Advances in Secondary Processing of Pharmaceutical Powders

Pharmaceuticals are becoming increasingly important in modern society. In most cases, active pharmaceutical ingredients (APIs) are formed through crystallisation but need to be combined with excipients to form a tablet, or with carriers to form an oral suspension. The formation of tablets requires s...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2024
Fag:
spiral jet mills
discrete element models
computational fluid dynamics
agent-based modeling and simulation
process modeling and simulation
tableting
product structures and characteristics
powder flow
die filling
powder rheology
dynamic cohesive index
excipients
continuous manufacturing
quality by design
mixing
coating
magnesium stearate
lubricant
Turbula
ProCepT
Mechanofusion
flowability
rheometry
flow energy
wet granulation
multicomponent
population balance model
content uniformity
powder agglomeration
Discrete Element Method
cohesion
twin-screw granulation
continuous mixing technology
vertical blender
direct compression
lubrication
material characterization
CFD-DEM simulation
wet particles
capillary force
viscous force
fluidized bed rotor granulator
pharmaceutical manufacturing
peptides
crystallization
powder mixing
amorphous solid dispersions
spray drying
L-leucine
bulk powder characterization
particle engineering
flowability enhancement
surface modification
continuous direct compression (CDC)
powder cohesion
loss in weight (LIW) feeding
blending
tabletting
continuous manufacture
triboelectric charging
electrostatics
DPI
DEM
inhalation
carrier-based formulation
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Online adgang:ONIX_20240514_9783725806782_427
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