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Molecular Mechanisms and Therapies of Colorectal Cancer 2.0

Colorectal cancer (CRC) is currently the third leading cause of cancer-related mortality. Transforming growth factor beta (TGF-β) signaling has been associated with CRC growth and metastasis due to its involvement in proliferation, epithelial-to-mesenchymal transition (EMT), and angiogenesis. The TG...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2024
Fag:
CD44
CD44v6
monoclonal antibody
colorectal cancer
exosome
cancer
exosomal miRNA
lncRNA
carcinogenesis
colon cancer
reactive oxygen species
sleep fragmentation
KRAS
NRAS
BRAF
microsatellite instability
HER2
colorectal cancer (CRC)
muscarinic acetylcholine receptor M3 (M3R) expression
human colorectal cancer survival
tissue microarray
immune cell markers
TIA-1
therapeutic target
synchronous metastatic colorectal cancer
liquid biopsy
PIK3CA
anti-EGFR
anti-VEGF
ABCG2
prognosis
survival
protein–protein interaction network
immunohistochemistry
qPCR
immune checkpoint inhibition
nivolumab
ipilimumab
metastatic colorectal cancer
FOXO
pictilisib
mucinous colorectal adenocarcinomas
molecular mechanisms
ATPase
autophagy
hepatocytes
liver
NAADP
biomarkers
bafilomycin A1
Ca2+ store
n/a
KRAS G12C colorectal cancer
mechanism of resistance
KRAS inhibitor
pocket
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
Online adgang:ONIX_20240514_9783725809516_544
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