Chapter 15 Brain Tumors and the Lynch Syndrome

Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and...

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Autors principals:	Peltomäki, Päivi, Gylling, Annette
Format:	Online
Idioma:	anglès
Publicat:	InTechOpen 2021
Matèries:	brain tumors lynch syndrome Colorectal cancer DNA methylation DNA mismatch repair Gene Glioblastoma Glioma Hereditary nonpolyposis colorectal cancer Mutation Neoplasm
Accés en línia:	612584
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