Chapter 15 Brain Tumors and the Lynch Syndrome
Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and...
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| Formato: | Online |
| Idioma: | inglés |
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InTechOpen
2021
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| Acceso en liña: | 612584 |
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| _version_ | 1869522756764172288 |
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| author | Peltomäki, Päivi Gylling, Annette |
| author_browse | Gylling, Annette Peltomäki, Päivi |
| author_facet | Peltomäki, Päivi Gylling, Annette |
| author_sort | Peltomäki, Päivi |
| collection | Directory of Open Access Books |
| description | Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by
germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most
prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal
cancers (Lynch & de la Chapelle, 2003). |
| format | Online |
| id | doab-20.500.12854ir-37172 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | InTechOpen |
| publisherStr | InTechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-371722025-05-09T09:46:47Z Chapter 15 Brain Tumors and the Lynch Syndrome Peltomäki, Päivi Gylling, Annette brain tumors lynch syndrome brain tumors lynch syndrome Colorectal cancer DNA methylation DNA mismatch repair Gene Glioblastoma Glioma Hereditary nonpolyposis colorectal cancer Mutation Neoplasm Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003). 2021-02-10T12:58:18Z 2019-10-04 14:27:25 2020-04-01T14:07:02Z 2016-08-01 23:55 2019-10-04 14:27:25 2020-04-01T14:07:02Z 2016-12-31 23:55:55 2019-10-04 14:27:25 2020-04-01T14:07:02Z 2011 chapter 612584 OCN: 1030821093 http://library.oapen.org/handle/20.500.12657/32348 https://directory.doabooks.org/handle/20.500.12854/37172 eng open access image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg n/a n/a n/a n/a n/a https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf https://library.oapen.org/bitstream/20.500.12657/32348/1/612584.pdf InTechOpen 10.5772/21293 10.5772/21293 035ecc65-6737-43cf-a13a-6bdf67ce01f4 Management of CNS Tumors FP7 Ideas: European Research Council 7292b17b-f01a-4016-94d3-d7fb5ef9fb79 European Research Council (ERC) EU collection 232635 FP7 open access |
| spellingShingle | brain tumors lynch syndrome brain tumors lynch syndrome Colorectal cancer DNA methylation DNA mismatch repair Gene Glioblastoma Glioma Hereditary nonpolyposis colorectal cancer Mutation Neoplasm Peltomäki, Päivi Gylling, Annette Chapter 15 Brain Tumors and the Lynch Syndrome |
| title | Chapter 15 Brain Tumors and the Lynch Syndrome |
| title_full | Chapter 15 Brain Tumors and the Lynch Syndrome |
| title_fullStr | Chapter 15 Brain Tumors and the Lynch Syndrome |
| title_full_unstemmed | Chapter 15 Brain Tumors and the Lynch Syndrome |
| title_short | Chapter 15 Brain Tumors and the Lynch Syndrome |
| title_sort | chapter 15 brain tumors and the lynch syndrome |
| topic | brain tumors lynch syndrome brain tumors lynch syndrome Colorectal cancer DNA methylation DNA mismatch repair Gene Glioblastoma Glioma Hereditary nonpolyposis colorectal cancer Mutation Neoplasm |
| topic_facet | brain tumors lynch syndrome brain tumors lynch syndrome Colorectal cancer DNA methylation DNA mismatch repair Gene Glioblastoma Glioma Hereditary nonpolyposis colorectal cancer Mutation Neoplasm |
| url | 612584 |
| work_keys_str_mv | AT peltomakipaivi chapter15braintumorsandthelynchsyndrome AT gyllingannette chapter15braintumorsandthelynchsyndrome |