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The Biology of Chronic Pain: Applications in Clinical Practice

Science has tremendously advanced our understanding of the pathophysiology of chronic pain. Breakthrough findings include functional and structural brain changes, neuro-inflammation, sensory changes, immune alterations, psychological problems, neurocognitive disorders, stress intolerance, sleep impa...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2024
Fag:
traumatic brain injury
headache
concussion
neuroinflammation
microglia
sleep
pain
Alzheimer’s
dementia
chronic pain
stress intolerance
autonomic nervous system
hypothalamus-pituitary-adrenal axis
genetics
epigenetics
sex differences
DNA methylation
pharmacogenetics
placebo effect
nocebo effect
expectation
conditioning
contextual factor
pain neuroscience education
epigenetic factors
neural factors
endocrine factors
immune factors
habituation
sensitization
migraine
fibromyalgia
chronic low back pain
cancer survivors
central sensitization
central sensitivity syndrome
insomnia
stress
precision medicine
chronification of pain
molecular markers
biomarkers
mechanisms
pediatric pain
developmental
peripheral sensitization
neuroimaging of pain
genetics and epigenetics of pain
neurophysiological markers
EEG
QST
back pain
muscle dysfunction
clinical implications
default mode network
salience network
ventromedial prefrontal cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Online adgang:ONIX_20240704_9783725813513_194
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Summary:Science has tremendously advanced our understanding of the pathophysiology of chronic pain. Breakthrough findings include functional and structural brain changes, neuro-inflammation, sensory changes, immune alterations, psychological problems, neurocognitive disorders, stress intolerance, sleep impairments, and (epi)genetic changes found in patients with chronic pain. This Journal of Clinical Medicine Boutique Special Issue focuses on the broad field of the biology of chronic pain in humans. It includes invited state-of-the-art papers addressing key biological processes in patients with chronic pain and original research reports. The state-of-the-art papers were written by leading experts and key opinion leaders in the field. This Special Issue contributes to an exciting area of tremendous advancements and breakthrough research.

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