The Biology of Chronic Pain: Applications in Clinical Practice

Science has tremendously advanced our understanding of the pathophysiology of chronic pain. Breakthrough findings include functional and structural brain changes, neuro-inflammation, sensory changes, immune alterations, psychological problems, neurocognitive disorders, stress intolerance, sleep impa...

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Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2024
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collection Directory of Open Access Books
description Science has tremendously advanced our understanding of the pathophysiology of chronic pain. Breakthrough findings include functional and structural brain changes, neuro-inflammation, sensory changes, immune alterations, psychological problems, neurocognitive disorders, stress intolerance, sleep impairments, and (epi)genetic changes found in patients with chronic pain. This Journal of Clinical Medicine Boutique Special Issue focuses on the broad field of the biology of chronic pain in humans. It includes invited state-of-the-art papers addressing key biological processes in patients with chronic pain and original research reports. The state-of-the-art papers were written by leading experts and key opinion leaders in the field. This Special Issue contributes to an exciting area of tremendous advancements and breakthrough research.
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institution Directory of Open Access Books
language eng
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1393982024-07-04T09:50:15Z The Biology of Chronic Pain: Applications in Clinical Practice Polli, Andrea Nijs, Jo traumatic brain injury headache concussion neuroinflammation microglia sleep pain Alzheimer’s dementia chronic pain stress intolerance autonomic nervous system hypothalamus-pituitary-adrenal axis genetics epigenetics sex differences DNA methylation pharmacogenetics placebo effect nocebo effect expectation conditioning contextual factor pain neuroscience education epigenetic factors neural factors endocrine factors immune factors habituation sensitization migraine fibromyalgia chronic low back pain cancer survivors central sensitization central sensitivity syndrome insomnia stress precision medicine chronification of pain molecular markers biomarkers mechanisms pediatric pain developmental peripheral sensitization neuroimaging of pain genetics and epigenetics of pain neurophysiological markers EEG QST back pain muscle dysfunction clinical implications default mode network salience network ventromedial prefrontal cortex thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Science has tremendously advanced our understanding of the pathophysiology of chronic pain. Breakthrough findings include functional and structural brain changes, neuro-inflammation, sensory changes, immune alterations, psychological problems, neurocognitive disorders, stress intolerance, sleep impairments, and (epi)genetic changes found in patients with chronic pain. This Journal of Clinical Medicine Boutique Special Issue focuses on the broad field of the biology of chronic pain in humans. It includes invited state-of-the-art papers addressing key biological processes in patients with chronic pain and original research reports. The state-of-the-art papers were written by leading experts and key opinion leaders in the field. This Special Issue contributes to an exciting area of tremendous advancements and breakthrough research. 2024-07-04T09:50:12Z 2024-07-04T09:50:12Z 2024 book ONIX_20240704_9783725813513_194 9783725813513 9783725813520 https://directory.doabooks.org/handle/20.500.12854/139398 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/9398 https://mdpi.com/books/pdfview/book/9398 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-1352-0 10.3390/books978-3-7258-1352-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725813513 9783725813520 200 open access
spellingShingle traumatic brain injury
headache
concussion
neuroinflammation
microglia
sleep
pain
Alzheimer’s
dementia
chronic pain
stress intolerance
autonomic nervous system
hypothalamus-pituitary-adrenal axis
genetics
epigenetics
sex differences
DNA methylation
pharmacogenetics
placebo effect
nocebo effect
expectation
conditioning
contextual factor
pain neuroscience education
epigenetic factors
neural factors
endocrine factors
immune factors
habituation
sensitization
migraine
fibromyalgia
chronic low back pain
cancer survivors
central sensitization
central sensitivity syndrome
insomnia
stress
precision medicine
chronification of pain
molecular markers
biomarkers
mechanisms
pediatric pain
developmental
peripheral sensitization
neuroimaging of pain
genetics and epigenetics of pain
neurophysiological markers
EEG
QST
back pain
muscle dysfunction
clinical implications
default mode network
salience network
ventromedial prefrontal cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
The Biology of Chronic Pain: Applications in Clinical Practice
title The Biology of Chronic Pain: Applications in Clinical Practice
title_full The Biology of Chronic Pain: Applications in Clinical Practice
title_fullStr The Biology of Chronic Pain: Applications in Clinical Practice
title_full_unstemmed The Biology of Chronic Pain: Applications in Clinical Practice
title_short The Biology of Chronic Pain: Applications in Clinical Practice
title_sort biology of chronic pain applications in clinical practice
topic traumatic brain injury
headache
concussion
neuroinflammation
microglia
sleep
pain
Alzheimer’s
dementia
chronic pain
stress intolerance
autonomic nervous system
hypothalamus-pituitary-adrenal axis
genetics
epigenetics
sex differences
DNA methylation
pharmacogenetics
placebo effect
nocebo effect
expectation
conditioning
contextual factor
pain neuroscience education
epigenetic factors
neural factors
endocrine factors
immune factors
habituation
sensitization
migraine
fibromyalgia
chronic low back pain
cancer survivors
central sensitization
central sensitivity syndrome
insomnia
stress
precision medicine
chronification of pain
molecular markers
biomarkers
mechanisms
pediatric pain
developmental
peripheral sensitization
neuroimaging of pain
genetics and epigenetics of pain
neurophysiological markers
EEG
QST
back pain
muscle dysfunction
clinical implications
default mode network
salience network
ventromedial prefrontal cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet traumatic brain injury
headache
concussion
neuroinflammation
microglia
sleep
pain
Alzheimer’s
dementia
chronic pain
stress intolerance
autonomic nervous system
hypothalamus-pituitary-adrenal axis
genetics
epigenetics
sex differences
DNA methylation
pharmacogenetics
placebo effect
nocebo effect
expectation
conditioning
contextual factor
pain neuroscience education
epigenetic factors
neural factors
endocrine factors
immune factors
habituation
sensitization
migraine
fibromyalgia
chronic low back pain
cancer survivors
central sensitization
central sensitivity syndrome
insomnia
stress
precision medicine
chronification of pain
molecular markers
biomarkers
mechanisms
pediatric pain
developmental
peripheral sensitization
neuroimaging of pain
genetics and epigenetics of pain
neurophysiological markers
EEG
QST
back pain
muscle dysfunction
clinical implications
default mode network
salience network
ventromedial prefrontal cortex
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url ONIX_20240704_9783725813513_194