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Oncology: From Empiricism to Integrative Biology

After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic...

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Enregistré dans:
Auteur principal: Thé, Hugues de
Format: Online
Langue:anglais
Publié: Collège de France 2024
Sujets:
oncology
cell biology
molecular biology
cancer
carcinogenesis
therapeutics
genetics
oncogenesis
biology
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFN Health, illness and addiction: social aspects
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
Accès en ligne:ONIX_20240916_9782722607750_29
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Résumé:After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic leukaemia. This treatment, which has cured virtually all patients, gives hope that the in-depth understanding of carcinogenesis mechanisms may lead to new therapeutic approaches that could be transposed to other cancers.

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