Oncology: From Empiricism to Integrative Biology

After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic...

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Hlavní autor: Thé, Hugues de
Médium: Online
Jazyk:angličtina
Vydáno: Collège de France 2024
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On-line přístup:ONIX_20240916_9782722607750_29
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author Thé, Hugues de
author_browse Thé, Hugues de
author_facet Thé, Hugues de
author_sort Thé, Hugues de
collection Directory of Open Access Books
description After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic leukaemia. This treatment, which has cured virtually all patients, gives hope that the in-depth understanding of carcinogenesis mechanisms may lead to new therapeutic approaches that could be transposed to other cancers.
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publishDate 2024
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spelling doab-20.500.12854ir-1448212024-09-16T09:41:15Z Oncology: From Empiricism to Integrative Biology Thé, Hugues de Libbrecht, Liz oncology cell biology molecular biology cancer carcinogenesis therapeutics genetics oncogenesis biology thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFN Health, illness and addiction: social aspects thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues After decades of descriptive studies, the biology of cancer is undergoing a real revolution: with genetic approaches, researchers have identified many of the cell deregulations likely to drive tumours. A treatment combining arsenic and retinoic acid targets the protein responsible for promyelocytic leukaemia. This treatment, which has cured virtually all patients, gives hope that the in-depth understanding of carcinogenesis mechanisms may lead to new therapeutic approaches that could be transposed to other cancers. 2024-09-16T09:41:13Z 2024-09-16T09:41:13Z 2024 book ONIX_20240916_9782722607750_29 2109-9235 9782722607750 https://directory.doabooks.org/handle/20.500.12854/144821 eng Leçons inaugurales image/jpeg n/a https://www.7switch.com/fr/ebook/9782722607750/from/openedition https://books.openedition.org/cdf/17573 Collège de France 10.4000/1209v 10.4000/1209v 1aaf812f-8953-49d7-becb-c2b3d34938a7 9782722607750 Paris open access
spellingShingle oncology
cell biology
molecular biology
cancer
carcinogenesis
therapeutics
genetics
oncogenesis
biology
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFN Health, illness and addiction: social aspects
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
Thé, Hugues de
Oncology: From Empiricism to Integrative Biology
title Oncology: From Empiricism to Integrative Biology
title_full Oncology: From Empiricism to Integrative Biology
title_fullStr Oncology: From Empiricism to Integrative Biology
title_full_unstemmed Oncology: From Empiricism to Integrative Biology
title_short Oncology: From Empiricism to Integrative Biology
title_sort oncology from empiricism to integrative biology
topic oncology
cell biology
molecular biology
cancer
carcinogenesis
therapeutics
genetics
oncogenesis
biology
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFN Health, illness and addiction: social aspects
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
topic_facet oncology
cell biology
molecular biology
cancer
carcinogenesis
therapeutics
genetics
oncogenesis
biology
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFN Health, illness and addiction: social aspects
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues
url ONIX_20240916_9782722607750_29
work_keys_str_mv AT thehuguesde oncologyfromempiricismtointegrativebiology