Recent Developments in the Synthesis and Functionalization of Nitrogen Heterocycles

The purpose of this reprint is to introduce the reader to the latest advances in the chemistry of N-heterocycles, such as the synthesis, reactivity, and applications of aromatic and saturated nitrogen heterocyclic compounds. The role of N-heterocycles in human life is difficult to overestimate; thei...

Descripció completa

Guardat en:

Dades bibliogràfiques
Format:	Online
Idioma:	anglès
Publicat:	MDPI - Multidisciplinary Digital Publishing Institute 2025
Matèries:	C–H functionalization cyclization indazole products transition metals catalysis nitro compounds Azolo[1,5-a]pyrimidines CK2 inhibition antitumor activity multicomponent reaction amides BF3·Et2O debenzylation nitrogen heterocycles 2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate anthranilamide ethyl levulinate Amberlyst® 15 Brønsted acid cascade reaction mechanochemistry quinazolinone ball mill azirines pyrrolines cycloaddition annulation copper catalysis nitro group nitropyridines bis-(het)aryl ethenes nucleophilic substitution thiols UV–Vis spectroscopy alkoxides aziridination manganese iminoiodinane energetic materials tetrazine hydroxytetrazole oxadiazole sulfonylureas DPP-IV inhibitors diabetes mellitus peptidomimetics alkynes enediynes heterocycles benzo[b]thiophene Bergman cyclization Nicholas reaction Sonogashira coupling benzenesulfonamides antifolates folic acids synthesis applications drugs aziridine non-activated nucleophilic ring-opening regioselectivity pyrrole domino reaction 1H-indole synthesis aza–Michael reaction SNAr reaction heteroaromatization 4-hydroxy-2-pyrone 4-pyridone aminoenone trifluoromethylated heterocycles regioselective reactions oxidative cyclization manganese(IV) oxide 1,2,4-triazine phenols cross-coupling spiropyrrolidine derivatives antimicrobial antioxidant antidiabetic ADME molecular docking and dynamic simulation sulfur–nitrogen heterocycles benzo[1,2-d:4,5-d’]bis([1,2,3]thiadiazole) aromatic nucleophilic substitution Suzuki and Stille cross-coupling reactions X-ray analysis estradiol benzisoxazole hybrid cancer selectivity apoptosis induction carborane tetrazole HEMDs DFT single crystal X-ray diffraction electrochemistry imidazoles vinyl azides click chemistry mechanochemical synthesis 1,2,3-triazole cycloaddition reaction Rufinamide synthesis solvent-free C-glycosyl compound amidrazone IEDDA pyridine aminofurazans fused furazans perchlorates energetic compound impact sensitivity thermal decomposition combustion burning rate 1,2,3-triazoles nucleobases Lewis acid molecular docking donor–acceptor cyclopropanes primary amines pyrrolidin-2-ones benz[g]indolizidines acetylenes amino acids C-H activation catalysis isoquinolones active methylene thioamides Michael addition dithiomalondianilide cyanoacetic esters [1,2]dithiolo[3,4-b]pyridines herbicide safeners azomethine ylide pyrrolidine spiro-compound imidazole medicinal chemistry drug discovery Minisci reaction heterogeneous photocatalysis N-hydroxyphthalimide titanium dioxide green chemistry visible light photocatalysis 2-hydroxyphenyl group hydrogen bond ESIPT luminescence [1,2,4]triazolo[4,3-c]quinazolines fluorescence solvatochromism pH-sensor multicomponent domino cyclizations ethyl trifluoropyruvate methyl ketones amino alcohols γ-lactams tetrahydropyrrolo[2,1-b]oxazolones tetrahydropyrrolo[2,1-b]oxazinones alkaloid Maillard reaction crystallization-induced diastereomer transformation glutamine hydroxy amino acid diketopiperazine thiourea dioxide TDO pyridazine pyrimidine pyrazine organophosphorus compounds dipyrroloquinoxaline bathochromic shift substituent effect energy gap N-trifluoromethyl group imidates iminonitriles nitrostyrenes 2-aminopyridine N-heterocycles 1,3,4-oxadiazole D-ribose L-amino acid pyrrole-2-carbaldehyde iodine effect antibacterial activity sustainable synthesis aromatic N-heterocycles solid acids nanoparticles microwaves ultrasounds visible light activation high hydrostatic pressure biomass 1,3-diynamides ynamides homogeneous catalysis annulation reactions cycloaddition cascade reactions helical twisted frontier molecular orbitals (Hel-FMO) Hexa-dehydro-Diels–Alder (HDDA) reaction quinolines indoles carbazoles N-heterocyclic-based dyes photosensitizers photodynamic therapy thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PH Physics::PHH Thermodynamics and heat
Accés en línia:	ONIX_20250220_9783725820818_103
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Descripció
Sumari:	The purpose of this reprint is to introduce the reader to the latest advances in the chemistry of N-heterocycles, such as the synthesis, reactivity, and applications of aromatic and saturated nitrogen heterocyclic compounds. The role of N-heterocycles in human life is difficult to overestimate; their diverse application spans from the pharmaceutical industry to the production of energetic materials, dyes, and non-linear optical materials, among many other areas. With this reprint, we aim to highlight the most recent and most promising research results in this field, presented in the form of original articles and high-quality reviews.

Recent Developments in the Synthesis and Functionalization of Nitrogen Heterocycles

Ítems similars