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Molecular Targets of Oxidative Stress

Oxidative stress, known to increase the risk of multiple metabolic and chronic disorders or cancer development, is defined as an imbalance between the production of reactive oxygen species (ROS) and the capacity of antioxidants to counteract the deleterious effects of oxidants. To regulate the oxida...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2025
Soggetti:
ASCT2
glutamate-glutamine cycle
glutaminase
glutamine synthase
glutathione synthetase
iNOS
S-nitrosylated cysteine
xCT
neurological manifestations
long-COVID
antioxidant enzymes
glutathione transferases
polymorphisms
Nrf2
spinal cord injury
phrenic motoneuron
AMPK
neuroinflammation
antioxidant
rat
NRF2
amyotrophic lateral sclerosis
C9orf72
dipeptide repeat proteins
obesity
lipid metabolism
chronic inflammation
oxidative stress
glucoraphanin
inflammatory bowel diseases
DSS
mitochondrial homeostasis
skeletal muscle
exercise
proteomics
radiation
low dose-rate
mesenchymal stem cells
human microvascular endothelial cells
RNAseq
gene regulation
Hsp90
ERK
JNK
Cdk5
Pin1
HO-1
phosphorylation
acetylation
ubiquitination
intracellular degradation
ligand-dependent stability
cancer
neurological disorders
exosomes
miRNA
non-pigmented ciliary epithelium
trabecular meshwork
primary open-angle glaucoma
Alzheimer’s disease
antioxidant response
electrophilic activators
multitargeting compounds
Nrf2 inducers
protein–protein interaction inhibitors
Parkinson’s disease
depression
Nuclear factor erythroid-2 (Nrf2)
pathophysiology
antioxidant pathways
Haemoxygenase (HO-1)
Nuclear factor kappa B (NF-κB)
rutin
UVA-induced damage
Nrf2 pathway
mitochondrial function
thyroid hormones
antioxidants
cardioprotection
THP-1-derived macrophages
alveolar macrophages
repetitive magnetic stimulation
p38 MAPK
p62
Nrf2 knockout mice
Keap1
Staphylococcus aureus
ferroptosis
metabolism
Ehretia tinifolia
anti-inflammatory
MAPK
NF-κB
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries
Accesso online:ONIX_20250220_9783725822270_172
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