Rotaviruses and Rotavirus Vaccines

Rotaviruses are a major cause of acute gastroenteritis in infants and young children and in the young of various mammalian and avian hosts. Although rotavirus-associated morbidity and mortality have significantly decreased since the introduction of rotavirus vaccines into childhood immunization prog...

Description complète

Enregistré dans:

Détails bibliographiques
Format:	Online
Langue:	anglais
Publié:	MDPI - Multidisciplinary Digital Publishing Institute 2025
Sujets:	rotavirus high-throughput screening microneutralization assay neutralizing antibody pre-existing immunity porcine rotavirus G5 virus isolation pathogenicity mRNA vaccine structural protein VP7 lipid nanoparticles reverse genetics expression vector rotavirus vaccine recombinant vaccine recombinant antigen structurally modified plant viruses tobacco mosaic virus plant virus adjuvants spherical particles porcine rotavirus A (RVA) serotypes molecular characteristics prevalence cross-species transmission Sub-Saharan Africa reverse genetics system triple-reassortant point mutation next-generation sequencing replication kinetics cell culture ML241 (hydrochloride) MAPK signaling pathway ERK1/2 NF-κB probiotics rotavirus infection histo-blood group antigens glycans diarrhea shedding viroplasm cytoskeleton microtubule actin molecular motors lipid droplets NSP5 NSP2 VP2 VP4 small-animal model nonstructural protein 2 particle assembly genome segment assortment genome packaging replication vaccine T cell regulatory T cell early life layered immunity rotavirus A, B, C P-type reassortment South Africa genotype serial passage culture adaptation gastroenteritis CNS sickness symptoms behavioral responses evolution rotavirus A G9P[4], G9P[6], NSP4 E6 genotype Mozambique antibody human rotavirus live attenuated rotavirus vaccine Rotarix® minigenome RNA-dependent RNA polymerase reporter assay maternal antibodies RV3-BB vaccine n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Accès en ligne:	ONIX_20250220_9783725827893_433
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Soyez le premier à ajouter un commentaire!

Rotaviruses and Rotavirus Vaccines

Documents similaires