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Molecular and Cellular Mechanisms of Cancers

This second Special Issue on the Molecular and Cellular Mechanisms of Glioblastoma presents 16 articles on the biology, genetics, and possible treatments against this devastating disease. Pathways to gliomagenesis and new targets were explored, along with epigenetic possibilities like the inhibition...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2025
Soggetti:
FABP6
invasion
angiogenesis
glioblastoma
corosolic acid
glioblastoma cell
invasiveness
AXL
CHIP
GAS6
JAK2
THC
CBD
microglia
astrocytes
melanoma
brain metastasis
glioblastoma-derived spheres
HDAC inhibitor
MEK inhibitor
radiation
combination therapy
single-cell
tumor microenvironment
copy number aberrations
DEPArray
DNA damage response
treatment resistance
temozolomide
XRN2
cell motility
tumor progression
glioblastomas
radioresistance
cancer stem cells
GPM6A
PTPRZ1
circular RNA
miRNA
brain tumor
medulloblastoma
pituitary adenoma
ependymoma
signaling pathway
diagnosis
treatment
ribosomal protein
reprogramming
extra-ribosomal function
microenvironment
glioma stem cell
ribosomal protein S6
ribosome biogenesis
transdifferentiation
plasticity
GBM subtypes
SHH signaling
Wnt/β-catenin signaling
Notch signaling
TGFβ signaling
BMP signaling
Hippo signaling
RA signaling
Oltipraz
apoptosis
anticancer therapeutic
glioblastoma organoids
glioblastoma spheroids
cerebral organoids
glioblastoma stem cells
drug screening
glycation
glioma
methylglyoxal
advanced glycation end-products
dormancy
stemness
Chemokine (C-C motif) Receptor-Like (CCRL)1
Schlafen (SLFN)13
Sloan-Kettering Institute (SKI)
Cdk5 and Abl Enzyme Substrate (Cables)1
Dachsous Cadherin-Related (DCHS)1
epigenetics
DNA methylation
n/a
reactive oxygen species
oxidative stress
natural polyphenols
fisetin
quercetin
redox-responsive transcription factors
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics
Accesso online:ONIX_20250220_9783725829361_497
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Riassunto:This second Special Issue on the Molecular and Cellular Mechanisms of Glioblastoma presents 16 articles on the biology, genetics, and possible treatments against this devastating disease. Pathways to gliomagenesis and new targets were explored, along with epigenetic possibilities like the inhibition of HDAC and the role of miRNA and circular RNA, tumor cell dormancy, cancer stem cells, and other approaches, to try to better understand and possibly combat glioblastoma.

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