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Neurodegenerative Disease

This Special Issue addresses the problem of treating neurodegenerative diseases from a variety of perspectives, from basic research into the molecular mechanisms responsible for a disease to reviews of the most advanced therapies available. This topic can provide exciting insights into new therapeut...

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Format: Online
Idioma:anglès
Publicat: MDPI - Multidisciplinary Digital Publishing Institute 2025
Matèries:
α-synuclein
lipids
Parkinson’s disease
post-translational modification
SERCA
positive allosteric modulators
calcium
Alzheimer’s disease
beta-amyloid
dendritic spines
calcium imaging
long-term potentiation
exosome
nasal lavage fluid
5XFAD
high-density multielectrode array
hippocampal slice
neural network
Alzheimer’s disease (AD)
Aging-Associated Cognitive Decline (AACD)
Amyloid Cascade Hypothesis 2.0 (ACH2.0)
intraneuronal Aβ (iAβ)
Aβ protein precursor (AβPP)
AβPP-independent iAβ production pathway
ACH2.0-based drugs
BACE1/BACE2 activators
mRNAs
RNA sequencing
transcriptome analysis
substantia nigra
regulatory T cells
Amyloid-β
status epilepticus
claustrum
endopiriform nucleus
claustroamygdaloid complex
neurodegeneration
ontogeny
polycystic ovary syndrome
PCOS
amyloid-associated proteins
conventional AD
unconventional AD
amyloid cascade hypothesis (ACH)
ACH-based models of AD
ACH-based AD drugs
ACH2.0
ACH2.0-based models of AD
histamine
dihydroergotamine
Morris water maze
novel object recognition
terminal nerve
olfactory dysfunctions
Kallmann syndrome
GnRH
SARS-CoV-2
lactacystin
GRP78
ER stress
neuroprotection
microglia
artemisinins
multitargeting neurotherapeutics
antisense oligonucleotides (ASOs)
motor neuron diseases
spinal muscular atrophy
amyotrophic lateral sclerosis
spinal and bulbar muscular atrophy
innovative therapy
nusinersen
tofersen
clinical trials
chronic inflammation
immune activation
neutrophil
extracellular traps
low-level LPS
IP injection
peripheral
brain
flow cytometry
microscopy
C57BL/6J
mice
timepoint optimization
inflammation
matrix metalloproteinase-3
ingenuity pathway analysis
gene set enrichment analysis
stroke
transcriptome
n/a
thema EDItEUR::M Medicine and Nursing
Accés en línia:ONIX_20250812T110751_9783725835089_48
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