Role of HER2
This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpr...
Gespeichert in:
| Format: | Online |
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| Sprache: | Englisch |
| Veröffentlicht: |
IntechOpen
2026
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| Schlagworte: | |
| Online-Zugang: | 3049-8864 |
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| Zusammenfassung: | This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpression, especially for breast cancer and beyond, in combination with other development therapies, antibody-drug conjugates, and overcomes resistance mechanisms. This book provides comprehensive coverage of the PI3K/AKT and MAPK signaling pathways, up-to-date information on next-generation HER2 inhibitors, including neratinib and tucatinib, and offers helpful advice for researchers and clinicians managing HER2-positive tumors. This book, which links laboratory findings with clinical applications and offers hope for better outcomes in HER2-driven cancers, is an essential resource for oncologists, molecular biologists, and pharmaceutical scientists. It does so clearly and understandably. |
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