Role of HER2
This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpr...
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| Formato: | Online |
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| Idioma: | inglês |
| Publicado em: |
IntechOpen
2026
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| Assuntos: | |
| Acesso em linha: | 3049-8864 |
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| _version_ | 1869528778974167040 |
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| collection | Directory of Open Access Books |
| description | This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpression, especially for breast cancer and beyond, in combination with other development therapies, antibody-drug conjugates, and overcomes resistance mechanisms. This book provides comprehensive coverage of the PI3K/AKT and MAPK signaling pathways, up-to-date information on next-generation HER2 inhibitors, including neratinib and tucatinib, and offers helpful advice for researchers and clinicians managing HER2-positive tumors. This book, which links laboratory findings with clinical applications and offers hope for better outcomes in HER2-driven cancers, is an essential resource for oncologists, molecular biologists, and pharmaceutical scientists. It does so clearly and understandably. |
| format | Online |
| id | doab-20.500.12854ir-171934 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1719342026-02-12T17:31:14Z Role of HER2 Riaz, Ammara Medical / Prosthesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics This book explores the crucial role that Human Epidermal Growth Factor Receptor 2 (HER2) plays in the initiation and progression of cancer, as well as cutting-edge molecular mechanisms, precision medicine, and novel targeted treatments, including lapatinib, pertuzumab, and trastuzumab. HER2 overexpression, especially for breast cancer and beyond, in combination with other development therapies, antibody-drug conjugates, and overcomes resistance mechanisms. This book provides comprehensive coverage of the PI3K/AKT and MAPK signaling pathways, up-to-date information on next-generation HER2 inhibitors, including neratinib and tucatinib, and offers helpful advice for researchers and clinicians managing HER2-positive tumors. This book, which links laboratory findings with clinical applications and offers hope for better outcomes in HER2-driven cancers, is an essential resource for oncologists, molecular biologists, and pharmaceutical scientists. It does so clearly and understandably. 2026-02-12T17:31:08Z 2026-02-12T17:31:08Z 2025 book 3049-8864 9781836344636 9781836344643 9781836344650 https://directory.doabooks.org/handle/20.500.12854/171934 eng Oncology image/jpeg n/a https://www.intechopen.com/books/1004447 https://intech-files.s3.amazonaws.com/a04Tc000008lIl3IAE/0016351_Authors_Book%20%282025-12-04%2012%3A35%3A30%29.pdf IntechOpen IntechOpen 10.5772/intechopen.1006255 10.5772/intechopen.1006255 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781836344636 9781836344643 9781836344650 IntechOpen 10 106 open access |
| spellingShingle | Medical / Prosthesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics Role of HER2 |
| title | Role of HER2 |
| title_full | Role of HER2 |
| title_fullStr | Role of HER2 |
| title_full_unstemmed | Role of HER2 |
| title_short | Role of HER2 |
| title_sort | role of her2 |
| topic | Medical / Prosthesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics |
| topic_facet | Medical / Prosthesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics |
| url | 3049-8864 |