Topoisomerases as Targets for Novel Drug Discovery

Topoisomerases play a crucial role in controlling DNA topology and have long been established as the therapeutic targets of several clinically successful antibacterial and anticancer drugs. Despite decades of clinical use, topoisomerase-targeting agents still face several limitations, including anti...

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Dades bibliogràfiques

Format:	Online
Idioma:	anglès
Publicat:	MDPI - Multidisciplinary Digital Publishing Institute 2026
Matèries:	Topoisomerase Type I topoisomerase Type II topoisomerase DNA Gyrase DNA topology Catalytic inhibitors Topo II poisons DNA gyrase inhibitors Anticancer agents Antibacterial agents thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Accés en línia:	ONIX_20260416T142754_9783725860814_21
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