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Biomimetic Radical Chemistry and Applications

The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an i...

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Autor principal: Chatgilialoglu, Chryssostomos
Formato: Online
Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2021
Assuntos:
QH301-705.5
Q1-390
gold nanoparticles
inhomogeneous reactions
chemical nuclease
liposomal somatostatin
replication fork stalling
lipid bilayer membranes
2c-3e S?S-bonded intermediates
cell micropolarity maps
protein labeling
time-resolved spectroscopy
1
pulse radiolysis
nucleosides
2-thiouracil
[1
lipidomics
radicals
reactive aldehydes
iron porphyrin
photolysis
oxidative damage
free fatty acids
charge transfer
fragmentation
biomimetic radical reaction
sulfones
bioinspired chemical catalysis
genomic and epigenomic instability
ATRPase
DNA methylation
oxononenal
trans lipid
copper
membrane fluidity maps
mitochondrial uncoupling protein
heme
thiyl radicals
oxidation
anomeric spironucleosides
protein stability
laser flash photolysis
type 2 diabetes
stationary radiolysis
confocal microscopy
iron(IV)-oxo
5]-radical translocation
diabetes
DNA hole transfer
free radical oxidation
radical reaction
kinetic studies
circular dichroism
catalase activity
thiobases
intercalation
electron transfer
iron-mediated ATRP
Fenton reaction
EPR spectroscopy
glycogen phosphorylase
azidoalkylation
free radicals
gamma radiolysis
quantum dynamics
hydrogen peroxide
carboazidation
?OH and ?N3 radicals
5?
oligonucleotides
Raman spectroscopy
azides
peroxidation
photo-ionization
guanine quadruplexes
8-cyclopurines
beta cells
cross-link
miRNAs
oxidative DNA damage
DNA damage
modified nucleosides
Julia–Kocienski olefination
DNA oxidation
therapeutic proteins
DNA replication stress
electron holes
singlet oxygen
radiosensitizers
cellular response
hydroxynonenal
isomerization
?-radiolysis
histone modifications
8-oxo-dG
6-dioxa-4-azaspiro[4.5]decane
retarded delivery
reaction mechanism
DNA
albumin
TD-DFT methods
nucleobase derivatives
bio-mimicking catalyst
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Acesso em linha:44857
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