Evolution of NK-mediated target recognition under the pressure of physiologic or pathologic stimuli

Since their discovery NK cells have come out as potential tools to fight cancer and viruses. This finding early urged different groups to study the mechanisms governing NK cell function. The identification of the MHC-I-specific inhibitory receptors (i.e. KIRs, NKG2A and certain Ly49 molecules) allow...

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Bibliographic Details
Main Authors: Miguel Lopez-Botet, Simona Sivori, Daniel Olive, Massimo Vitale
Format: Online
Language:English
Published: Frontiers Media SA 2021
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Online Access:18598
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