PI3K signalling

The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the r...

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Bibliografski detalji

Glavni autori:	Martin Turner, Klaus Okkenhaug, Michael R. Gold
Format:	Online
Jezik:	engleski
Izdano:	Frontiers Media SA 2021
Teme:	R5-920 RC581-607 B cell PI3K/AKT/mTOR Signal Transduction T cell PI3K pathway inhibitors thema EDItEUR::M Medicine and Nursing
Online pristup:	17811
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