The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance
The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mT...
Sábháilte in:
| Príomhchruthaitheoirí: | , , |
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| Formáid: | Online |
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
Frontiers Media SA
2021
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| Ábhair: | |
| Rochtain ar líne: | 18889 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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| _version_ | 1869521495215046656 |
|---|---|
| author | Geraldo Aleixo Passos Ernna Herida Oliveira Daniella Areas Mendes-da-Cruz |
| author_browse | Daniella Areas Mendes-da-Cruz Ernna Herida Oliveira Geraldo Aleixo Passos |
| author_facet | Geraldo Aleixo Passos Ernna Herida Oliveira Daniella Areas Mendes-da-Cruz |
| author_sort | Geraldo Aleixo Passos |
| collection | Directory of Open Access Books |
| description | The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mTECs). It includes one Editorial and 12 other excellent contributions in the format of mini reviews or original research papers covering one or more of these aspects: promiscuous gene expression (PGE), epigenetics, miRNAs, association of the Aire gene and miRNAs, thymocyte–TEC interaction, coxsackievirus and type 1 diabetes, exosomes in the thymus, thymic crosstalk, thymic B cells, T cell development, chemokines and migration of T cells, miRNAs and the thymic atrophy, cell–cell interactions, and thymus ontogeny. Authors raised hypothesis, discuss concepts, and show open questions. The remaining important issues to resolve questions within the central tolerance research are briefly discussed below. |
| format | Online |
| id | doab-20.500.12854ir-58575 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-585752024-03-30T23:22:52Z The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance Geraldo Aleixo Passos Ernna Herida Oliveira Daniella Areas Mendes-da-Cruz R5-920 RC581-607 thymic crosstalk Central Tolerance promiscuous gene expression Aire gene cell-cell interaction thymocyte microRNA Thymic B cell Chemokines Thymus thema EDItEUR::M Medicine and Nursing The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mTECs). It includes one Editorial and 12 other excellent contributions in the format of mini reviews or original research papers covering one or more of these aspects: promiscuous gene expression (PGE), epigenetics, miRNAs, association of the Aire gene and miRNAs, thymocyte–TEC interaction, coxsackievirus and type 1 diabetes, exosomes in the thymus, thymic crosstalk, thymic B cells, T cell development, chemokines and migration of T cells, miRNAs and the thymic atrophy, cell–cell interactions, and thymus ontogeny. Authors raised hypothesis, discuss concepts, and show open questions. The remaining important issues to resolve questions within the central tolerance research are briefly discussed below. 2021-02-12T02:27:13Z 2021-02-12T02:27:13Z 2016-04-07 11:22:02 2016 book 18889 16648714 9782889197705 https://directory.doabooks.org/handle/20.500.12854/58575 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/The_Role_of_Aire_microRNAs_and_Cell-Cell_Interactions_on_Thymic_Architecture_and_Induction_of_Toler/795#nogo http://journal.frontiersin.org/researchtopic/3221/the-role-of-aire-micrornas-and-cell-cell-interactions-on-thymic-architecture-and-induction-of-tolera Frontiers Media SA 10.3389/978-2-88919-770-5 10.3389/978-2-88919-770-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889197705 107 open access |
| spellingShingle | R5-920 RC581-607 thymic crosstalk Central Tolerance promiscuous gene expression Aire gene cell-cell interaction thymocyte microRNA Thymic B cell Chemokines Thymus thema EDItEUR::M Medicine and Nursing Geraldo Aleixo Passos Ernna Herida Oliveira Daniella Areas Mendes-da-Cruz The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance |
| title | The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance |
| title_full | The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance |
| title_fullStr | The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance |
| title_full_unstemmed | The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance |
| title_short | The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance |
| title_sort | role of aire micrornas and cell cell interactions on thymic architecture and induction of tolerance |
| topic | R5-920 RC581-607 thymic crosstalk Central Tolerance promiscuous gene expression Aire gene cell-cell interaction thymocyte microRNA Thymic B cell Chemokines Thymus thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC581-607 thymic crosstalk Central Tolerance promiscuous gene expression Aire gene cell-cell interaction thymocyte microRNA Thymic B cell Chemokines Thymus thema EDItEUR::M Medicine and Nursing |
| url | 18889 |
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